Literature DB >> 9372512

Protective immunity induced by vaccination with two Haemonchus contortus excretory secretory proteins in sheep.

H D Schallig1, M A van Leeuwen, A W Cornelissen.   

Abstract

Two excretory secretory (ES) antigens of adult Haemonchus contortus with molecular weights of 15 and 24 kDa, respectively, were evaluated as protective immunogen against haemonchosis. Sheep were vaccinated three times and subsequently challenged with 20,000 infective larvae. Vaccination induced significant reduction (> 70%) in mean faecal egg counts and abomasal worm burden compared to the non-vaccinated control group or adjuvant control group. Vaccination induced ES-specific antibodies and stimulated infiltration of mast cells in the abomasal tissue.

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Year:  1997        PMID： 9372512     DOI： 10.1046/j.1365-3024.1997.d01-148.x

Source DB:  PubMed          Journal:  Parasite Immunol        ISSN： 0141-9838            Impact factor:   2.280


  23 in total

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Review 3.  Human hookworm infection in the 21st century.

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Authors:  L García-Coiradas; F Angulo-Cubillán; S Méndez; V Larraga; C de la Fuente; M Cuquerella; J M Alunda
Journal:  Parasitol Res       Date:  2008-09-30       Impact factor: 2.289

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Journal:  Int J Nanomedicine       Date:  2021-05-04

7.  The influence of MHC and immunoglobulins a and e on host resistance to gastrointestinal nematodes in sheep.

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Journal:  J Parasitol Res       Date:  2011-04-12

Review 8.  Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity.

Authors:  James P Hewitson; John R Grainger; Rick M Maizels
Journal:  Mol Biochem Parasitol       Date:  2009-05-03       Impact factor: 1.759

9.  An AC-5 cathepsin B-like protease purified from Haemonchus contortus excretory secretory products shows protective antigen potential for lambs.

Authors:  Erik De Vries; Nicole Bakker; Jeroen Krijgsveld; Dave P Knox; Albert J R Heck; Ana Patricia Yatsuda
Journal:  Vet Res       Date:  2009-04-30       Impact factor: 3.683

10.  Inhibition of Haemonchus contortus larval development by fungal lectins.

Authors:  Christian Heim; Hubertus Hertzberg; Alex Butschi; Silvia Bleuler-Martinez; Markus Aebi; Peter Deplazes; Markus Künzler; Saša Štefanić
Journal:  Parasit Vectors       Date:  2015-08-19       Impact factor: 3.876
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