Literature DB >> 935855

Cross-linking of DNA in situ as a probe for chromatin structure.

C V Hanson, C K Shen, J E Hearst.   

Abstract

The photochemical cross-linking of DNA in situ in chromatin is blocked over short intervals. Electron microscopy of DNA cross-linked in chromatin reveals the lengths of protected regions and provides a map of their sites along the DNA. Protected regions occur most frequently in tandem and have a basic length of 160 to 200 base pairs.

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Year:  1976        PMID: 935855     DOI: 10.1126/science.935855

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  35 in total

Review 1.  Half a century of "the nuclear matrix".

Authors:  T Pederson
Journal:  Mol Biol Cell       Date:  2000-03       Impact factor: 4.138

2.  Ribosomal gene clusters are uniquely proportioned between open and closed chromatin structures in both tomato leaf cells and exponentially growing suspension cultures.

Authors:  A Conconi; J M Sogo; C A Ryan
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

3.  Production of DNA bifilarly substituted with bromodeoxyuridine in the first round of synthesis: branch migration during isolation of cellular DNA.

Authors:  K Tatsumi; B Strauss
Journal:  Nucleic Acids Res       Date:  1978-02       Impact factor: 16.971

4.  Photochemical addition of the cross-linking reagent 4,5', 8-trimethylpsoralen (trioxaslen) to intracellular and viral simian virus 40 DNA-histone complexes.

Authors:  L M Hallick; H A Yokota; J C Bartholomew; J E Hearst
Journal:  J Virol       Date:  1978-07       Impact factor: 5.103

5.  Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences.

Authors:  T R Cech; M L Pardue
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

6.  High resolution psoralen mapping reveals an altered DNA helical structure in the SV40 regulatory region.

Authors:  E A Ostrander; R A Karty; L M Hallick
Journal:  Nucleic Acids Res       Date:  1988-01-11       Impact factor: 16.971

7.  Photochemical crosslinking of transcription complexes with psoralen. I. Covalent attachment of in vitro SV40 nascent RNA to its double-stranded DNA template.

Authors:  C K Shen; J E Hearst
Journal:  Nucleic Acids Res       Date:  1978-04       Impact factor: 16.971

8.  In vivo mapping of nucleosomes using psoralen-DNA crosslinking and primer extension.

Authors:  R E Wellinger; J M Sogo
Journal:  Nucleic Acids Res       Date:  1998-03-15       Impact factor: 16.971

9.  Analysis of the psoralen-crosslinking pattern in chromatin DNA by exonuclease digestion.

Authors:  R M Widmer; T Koller; J M Sogo
Journal:  Nucleic Acids Res       Date:  1988-07-25       Impact factor: 16.971

10.  Method of mapping DNA replication origins.

Authors:  L D Spotila; J A Huberman
Journal:  Mol Cell Biol       Date:  1985-01       Impact factor: 4.272

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