Literature DB >> 9358351

Moral assessment of growth hormone therapy for children with idiopathic short stature.

M Verweij1, F Kortmann.   

Abstract

The prescription of growth hormone therapy for children who are not growth hormone deficient is one of the controversies in contemporary paediatric endocrinology. Is it morally appropriate to enhance the growth, by means of medical treatment, of a child wish idiopathic short stature? The medical, moral, and philosophical questions in this area are many. Data on the effects of human growth hormone (hGH) treatment will not on their own provide us with answers, as these effects have to be evaluated from a normative perspective. In this article we consider hGH treatment for children of idiopathic short stature from three normative perspectives: the goals of medicine, the good of the patient, and the public good. We argue that the prevention of psychological and social problems due to short stature (and not merely the enhancement of growth) should be the ultimate goal of medical treatment and research.

Entities:  

Keywords:  Analytical Approach; Biomedical Enhancement; Health Care and Public Health; Professional Patient Relationship

Mesh:

Substances:

Year:  1997        PMID: 9358351      PMCID: PMC1377370          DOI: 10.1136/jme.23.5.305

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  9 in total

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Authors:  C J Kelnar
Journal:  Acta Paediatr Scand Suppl       Date:  1990

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Authors:  I K Zola
Journal:  Sociol Rev       Date:  1972-11

3.  Short children, anxious parents: is growth hormone the answer?

Authors:  M Benjamin; J Muyskens; P Saenger
Journal:  Hastings Cent Rep       Date:  1984-04       Impact factor: 2.683

4.  Human growth hormone: the dilemma of expanded use in children.

Authors:  G B White
Journal:  Kennedy Inst Ethics J       Date:  1993-12

5.  Human growth hormone: a case study in treatment priorities.

Authors:  Carol A Tauer
Journal:  Hastings Cent Rep       Date:  1995 May-Jun       Impact factor: 2.683

Review 6.  Therapeutic controversies: growth hormone (GH) treatment of non-GH deficient subjects.

Authors:  D B Allen; C G Brook; N A Bridges; P C Hindmarsh; H J Guyda; D Frazier
Journal:  J Clin Endocrinol Metab       Date:  1994-11       Impact factor: 5.958

7.  Long-term results of growth hormone therapy in children with short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group.

Authors:  J M Wit; B Boersma; S M de Muinck Keizer-Schrama; H E Nienhuis; W Oostdijk; B J Otten; H A Delemarre-Van de Waal; M Reeser; J J Waelkens; B Rikken
Journal:  Clin Endocrinol (Oxf)       Date:  1995-04       Impact factor: 3.478

Review 8.  Use and abuse of human growth hormone.

Authors:  E K Neely; R G Rosenfeld
Journal:  Annu Rev Med       Date:  1994       Impact factor: 13.739

9.  Growth response of children with non-growth-hormone deficiency and marked short stature during three years of growth hormone therapy.

Authors:  N J Hopwood; R L Hintz; J M Gertner; K M Attie; A J Johanson; J Baptista; J Kuntze; R M Blizzard; J F Cara; S D Chernausek
Journal:  J Pediatr       Date:  1993-08       Impact factor: 4.406

  9 in total
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Journal:  J Med Ethics       Date:  2005-09       Impact factor: 2.903

2.  Combining multicriteria decision analysis, ethics and health technology assessment: applying the EVIDEM decision-making framework to growth hormone for Turner syndrome patients.

Authors:  Mireille M Goetghebeur; Monika Wagner; Hanane Khoury; Donna Rindress; Jean-Pierre Grégoire; Cheri Deal
Journal:  Cost Eff Resour Alloc       Date:  2010-04-08

Review 3.  "Anything you can do, I can do bigger?": the ethics and equity of growth hormone for small normal children.

Authors:  D G Gill
Journal:  Arch Dis Child       Date:  2006-03       Impact factor: 3.791

4.  Medicalising short children with growth hormone? Ethical considerations of the underlying sociocultural aspects.

Authors:  Maria Cristina Murano
Journal:  Med Health Care Philos       Date:  2018-06
  4 in total

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