Literature DB >> 16492893

"Anything you can do, I can do bigger?": the ethics and equity of growth hormone for small normal children.

D G Gill1.   

Abstract

This paper argues against the use of growth hormone (GH) for small normal children ("idiopathic" short stature) with the following considerations: ethical (philosophical) grounds, cost-economic implications, and the rationale for treating normal physiological variation with a potent pharmacological agent. The author would prefer to see health and economic resources being directed to correct nutritional and environmental deprivation among underprivileged groups in preference to providing GH injections for small normal children.

Entities:  

Keywords:  Analytical Approach; Health Care and Public Health

Mesh:

Substances:

Year:  2006        PMID: 16492893      PMCID: PMC2065932          DOI: 10.1136/adc.2005.081778

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  15 in total

1.  Growth hormone use in normal, short children--a plea for reason.

Authors:  S E Oberfield
Journal:  N Engl J Med       Date:  1999-02-18       Impact factor: 91.245

Review 2.  hGH for short stature: ethical issues raised by expanded access.

Authors:  David B Allen; Norman Fost
Journal:  J Pediatr       Date:  2004-05       Impact factor: 4.406

Review 3.  Growth hormone therapy for short stature: panacea or Pandora's box?

Authors:  D B Allen; N C Fost
Journal:  J Pediatr       Date:  1990-07       Impact factor: 4.406

4.  Effects of social class differences and social mobility on growth in height, weight and body mass index in a British cohort.

Authors:  G W Lasker; C G Mascie-Taylor
Journal:  Ann Hum Biol       Date:  1989 Jan-Feb       Impact factor: 1.533

5.  Considerations related to the use of recombinant human growth hormone in children. American Academy of Pediatrics Committee on Drugs and Committee on Bioethics.

Authors: 
Journal:  Pediatrics       Date:  1997-01       Impact factor: 7.124

6.  Moral assessment of growth hormone therapy for children with idiopathic short stature.

Authors:  M Verweij; F Kortmann
Journal:  J Med Ethics       Date:  1997-10       Impact factor: 2.903

7.  Growth hormone (GH) treatment to final height in children with idiopathic short stature: evidence for a dose effect.

Authors:  Jan M Wit; Lyset T M Rekers-Mombarg; Gordon B Cutler; Brenda Crowe; Tracy J Beck; Kristen Roberts; Anne Gill; Jean-Louis Chaussain; Herwig Frisch; Rafael Yturriaga; Andrea F Attanasio
Journal:  J Pediatr       Date:  2005-01       Impact factor: 4.406

Review 8.  The psychological burden of short stature: evidence against.

Authors:  Linda D Voss; David E Sandberg
Journal:  Eur J Endocrinol       Date:  2004-08       Impact factor: 6.664

Review 9.  Psychosocial correlates of short stature and delayed puberty.

Authors:  P D Lee; R G Rosenfeld
Journal:  Pediatr Clin North Am       Date:  1987-08       Impact factor: 3.278

10.  Adult body height and childhood socioeconomic group in the Swedish population.

Authors:  A M Peck; D H Vågerö
Journal:  J Epidemiol Community Health       Date:  1987-12       Impact factor: 3.710

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  2 in total

1.  Responding to requests from adult patients for neuroenhancements: guidance of the Ethics, Law and Humanities Committee.

Authors:  Dan Larriviere; Michael A Williams; Matt Rizzo; Richard J Bonnie
Journal:  Neurology       Date:  2009-09-23       Impact factor: 9.910

2.  Medicalising short children with growth hormone? Ethical considerations of the underlying sociocultural aspects.

Authors:  Maria Cristina Murano
Journal:  Med Health Care Philos       Date:  2018-06
  2 in total

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