Literature DB >> 9332160

Quantification of historical dust exposures in the diatomaceous earth industry.

N S Seixas1, N J Heyer, E A Welp, H Checkoway.   

Abstract

Quantitative estimates of dust exposure in a diatomaceous earth (DE) mining and milling operation have been derived based on air sampling records for the period 1948-1988. A total of 6395 records was included in the analysis. Conversion of results obtained by particle counting, expressed as millions of particles per cubic feet (mppcf) of gravimetrically from a filter cassette and expressed as mg m-3 total, were converted to mg m-3 respirable dust using a conversion factor derived from data obtained during the same periods at the plant. Conversion factors were calculated as the average difference of means on the log scale in order to provide stable and consistent conversions and as a ratio of arithmetic means so that the results could be compared with similar studies. After converting the available data to mg m-3 respirable dust, geometric mean (geometric standard deviation) concentrations were 0.37 (2.43) during the 1950s and 0.17 (2.35) during later periods. Exposures were estimated using two linear models, one estimating the changes in concentration over time, and the other providing job-specific mean exposures during the more recent period. Extrapolation of the estimates to periods prior to the availability of any data was done using a subjectively-determined scaling factor. The average estimated respirable dust concentrations for 135 jobs were 3.55 (+/-1.25), 1.37 (+/-0.48), 0.47 (+/-0.16) and 0.29 (+/-0.10) mg m-3 prior to 1949, 1949-1953, 1954-1973 and 1974-1988, respectively. Despite the limitations of the available data, the estimation procedures used are expected to provide reasonable quantitative estimates of silica-containing dust exposure for subsequent exposure-response analyses.

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Year:  1997        PMID: 9332160     DOI: 10.1016/S0003-4878(97)00009-4

Source DB:  PubMed          Journal:  Ann Occup Hyg        ISSN: 0003-4878


  10 in total

1.  Crystalline silica exposure, radiological silicosis, and lung cancer mortality in diatomaceous earth industry workers.

Authors:  H Checkoway; J M Hughes; H Weill; N S Seixas; P A Demers
Journal:  Thorax       Date:  1999-01       Impact factor: 9.139

2.  Exposure-response analysis and risk assessment for silica and silicosis mortality in a pooled analysis of six cohorts.

Authors:  A 't Mannetje; K Steenland; M Attfield; P Boffetta; H Checkoway; N DeKlerk; R-S Koskela
Journal:  Occup Environ Med       Date:  2002-11       Impact factor: 4.402

Review 3.  Smoothing in occupational cohort studies: an illustration based on penalised splines.

Authors:  E A Eisen; I Agalliu; S W Thurston; B A Coull; H Checkoway
Journal:  Occup Environ Med       Date:  2004-10       Impact factor: 4.402

4.  Crystalline silica exposure and lung cancer mortality in diatomaceous earth industry workers: a quantitative risk assessment.

Authors:  F L Rice; R Park; L Stayner; R Smith; S Gilbert; H Checkoway
Journal:  Occup Environ Med       Date:  2001-01       Impact factor: 4.402

5.  Exposure to crystalline silica, silicosis, and lung disease other than cancer in diatomaceous earth industry workers: a quantitative risk assessment.

Authors:  R Park; F Rice; L Stayner; R Smith; S Gilbert; H Checkoway
Journal:  Occup Environ Med       Date:  2002-01       Impact factor: 4.402

6.  Occupational silica exposure and mortality from lung cancer and nonmalignant respiratory disease: G-estimation of structural nested accelerated failure time models.

Authors:  Sally Picciotto; Andreas M Neophytou; Daniel M Brown; Harvey Checkoway; Ellen A Eisen; Sadie Costello
Journal:  Environ Epidemiol       Date:  2018-09-12

7.  Exposure to inhalable, respirable, and ultrafine particles in welding fume.

Authors:  Martin Lehnert; Beate Pesch; Anne Lotz; Johannes Pelzer; Benjamin Kendzia; Katarzyna Gawrych; Evelyn Heinze; Rainer Van Gelder; Ewald Punkenburg; Tobias Weiss; Markus Mattenklott; Jens-Uwe Hahn; Carsten Möhlmann; Markus Berges; Andrea Hartwig; Thomas Brüning
Journal:  Ann Occup Hyg       Date:  2012-04-26

8.  The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation.

Authors:  C Nattrass; C J Horwell; D E Damby; A Kermanizadeh; D M Brown; V Stone
Journal:  J Occup Med Toxicol       Date:  2015-07-10       Impact factor: 2.646

9.  Exposure-Lag-Response in Longitudinal Studies: Application of Distributed-Lag Nonlinear Models in an Occupational Cohort.

Authors:  Andreas M Neophytou; Sally Picciotto; Daniel M Brown; Lisa E Gallagher; Harvey Checkoway; Ellen A Eisen; Sadie Costello
Journal:  Am J Epidemiol       Date:  2018-07-01       Impact factor: 4.897

10.  Estimating Counterfactual Risk Under Hypothetical Interventions in the Presence of Competing Events: Crystalline Silica Exposure and Mortality From 2 Causes of Death.

Authors:  Andreas M Neophytou; Sally Picciotto; Daniel M Brown; Lisa E Gallagher; Harvey Checkoway; Ellen A Eisen; Sadie Costello
Journal:  Am J Epidemiol       Date:  2018-09-01       Impact factor: 4.897

  10 in total

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