Literature DB >> 9332007

Synthesis of Tn and sialyl Tn antigen-lipid A analog conjugates for synthetic vaccines.

K Miyajima1, T Nekado, K Ikeda, K Achiwa.   

Abstract

Conjugates of Tn and sialyl Tn antigen with N-teradecanoyl L-seryl-beta-alanine-containing D-glucosamine derivatives structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers or HIV.

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Year:  1997        PMID： 9332007     DOI： 10.1248/cpb.45.1544

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  4 in total

1.  Synthesis of a C-glycoside analogue of sTn: an HIV- and tumor-associated antigen.

Authors:  Balagurunathan Kuberan; Sulthan A Sikkander; Hiroshi Tomiyama; Robert J Linhardt
Journal:  Angew Chem Int Ed Engl       Date:  2003-05-09       Impact factor: 15.336

2.  Synthesis of double C-glycoside analogue of sTn.

Authors:  Dino K Ress; Sultan N Baytas; Qun Wang; Eva M Muñoz; Kazuo Tokuzoki; Hiroshi Tomiyama; Robert J Linhardt
Journal:  J Org Chem       Date:  2005-09-30       Impact factor: 4.354

3.  Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives.

Authors:  Li Ding; Hai Yu; Kam Lau; Yanhong Li; Saddam Muthana; Junru Wang; Xi Chen
Journal:  Chem Commun (Camb)       Date:  2011-07-01       Impact factor: 6.222

Review 4.  Recent Advances in Toll Like Receptor-Targeting Glycoconjugate Vaccines.

Authors:  Qingjiang Li; Zhongwu Guo
Journal:  Molecules       Date:  2018-06-29       Impact factor: 4.411
  4 in total

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