Literature DB >> 9331573

Combined chromosome microdissection and comparative genomic hybridization detect multiple sites of amplification DNA in a human lung carcinoma cell line.

T Taguchi1, G Z Cheng, D W Bell, B Balsara, Z Liu, J M Siegfried, J R Testa.   

Abstract

Chromosome microdissection-fluorescence in situ hybridization and comparative genomic hybridization (CGH) were performed in parallel to identify the native location of amplified DNA in a human non-small cell lung cancer (NSCLC) cell line exhibiting a homogeneously staining region (hsr) and double minutes (dmin). The native locations of microdissected DNA from the hsr and dmin were 7p12-13 and 8q24, respectively. Southern analysis revealed coamplification of EGFR (7p12) and MYC (8q24). CGH detected amplification of DNA not only from 7p12-13 and 8q24, but also from 9p24 and 10q22.

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Year:  1997        PMID： 9331573     DOI： 10.1002/(sici)1098-2264(199710)20:2<208::aid-gcc13>3.0.co;2-m

Source DB:  PubMed          Journal:  Genes Chromosomes Cancer        ISSN： 1045-2257            Impact factor:   5.006


  6 in total

Review 1.  Comparative genomic hybridisation.

Authors:  M M Weiss; M A Hermsen; G A Meijer; N C van Grieken; J P Baak; E J Kuipers; P J van Diest
Journal:  Mol Pathol       Date:  1999-10

2.  A probe generated by chromosome microdissection, useful for analyzing Y chromosome evolution in Old World monkeys.

Authors:  Takahiro Taguchi; Kunihiro Akimaru; Hirohisa Hirai; Yuriko Hirai; Jason M Mwenda; Kazunari Yuri
Journal:  Chromosome Res       Date:  2003       Impact factor: 5.239

3.  Multiple sites of highly amplified DNA sequences detected by molecular cytogenetic analysis in HS-RMS-2, a new pleomorphic rhabdomyosarcoma cell line.

Authors:  Eiji Takaoka; Hiroshi Sonobe; Kunihiro Akimaru; Shuji Sakamoto; Taro Shuin; Masanori Daibata; Takahiro Taguchi; Akira Tominaga
Journal:  Am J Cancer Res       Date:  2012-02-19       Impact factor: 6.166

Review 4.  Small nucleolar RNAs in cancer.

Authors:  Kaiissar Mannoor; Jipei Liao; Feng Jiang
Journal:  Biochim Biophys Acta       Date:  2012-04-03

5.  Genomic profiles in stage I primary non small cell lung cancer using comparative genomic hybridization analysis of cDNA microarrays.

Authors:  Feng Jiang; Zhengnan Yin; Nancy P Caraway; Ruiyun Li; Ruth L Katz
Journal:  Neoplasia       Date:  2004 Sep-Oct       Impact factor: 5.715

6.  A novel amplicon at 9p23 - 24 in squamous cell carcinoma of the esophagus that lies proximal to GASC1 and harbors NFIB.

Authors:  Z Q Yang; I Imoto; A Pimkhaokham; Y Shimada; K Sasaki; M Oka; J Inazawa
Journal:  Jpn J Cancer Res       Date:  2001-04
  6 in total

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