Literature DB >> 9323718

The development of subretinal microphotodiodes for replacement of degenerated photoreceptors.

E Zrenner1, K D Miliczek, V P Gabel, H G Graf, E Guenther, H Haemmerle, B Hoefflinger, K Kohler, W Nisch, M Schubert, A Stett, S Weiss.   

Abstract

There are presently several concepts to restore vision in blind or highly visually handicapped persons by implanting electronic devices into the eye in order to partially restore vision. Here, the approach to replace retinal photoreceptors by a subretinally implanted microphotodiode array (MPDA) is summarized. A survey is given on the present state of the development of MPDAs, the possibility of in vitro and in vivo tests as well as first results on biocompatibility and histology. Additionally, electrophysiological recordings in rabbits and rats are presented which have received such subretinal implants.

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Year:  1997        PMID： 9323718     DOI： 10.1159/000268025

Source DB:  PubMed          Journal:  Ophthalmic Res        ISSN： 0030-3747            Impact factor:   2.892


  27 in total

Review 1.  Treatment of subfoveal choroidal neovascularisation in age related macular degeneration: focus on clinical application of verteporfin photodynamic therapy.

Authors:  G Soubrane; N M Bressler
Journal:  Br J Ophthalmol       Date:  2001-04       Impact factor: 4.638

2.  Towards the cortical representation of form and motion stimuli generated by a retina implant.

Authors:  Thomas Schanze; Nina Greve; Lutz Hesse
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-07-29       Impact factor: 3.117

Review 3.  Retinal replacement--the development of microelectronic retinal prostheses--experience with subretinal implants and new aspects.

Authors:  Helmut G Sachs; Veit-Peter Gabel
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-08-10       Impact factor: 3.117

4.  Direct stimulation of optic nerve by electrodes implanted in optic disc of rabbit eyes.

Authors:  Xiaoyun Fang; Hirokazu Sakaguchi; Takashi Fujikado; Makoto Osanai; Hiroyuki Kanda; Yasushi Ikuno; Motohiro Kamei; Masahito Ohji; Dekang Gan; Junsub Choi; Tetsuya Yagi; Yasuo Tano
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-09-17       Impact factor: 3.117

5.  Repeated transchoroidal implantation and explantation of compound subretinal prostheses: an exploratory study in rabbits.

Authors:  Florian Gekeler; Karin Kobuch; Georgios Blatsios; Eberhart Zrenner; Kei Shinoda
Journal:  Jpn J Ophthalmol       Date:  2010-11-05       Impact factor: 2.447

6.  Ethical considerations for volunteer recruitment of visual prosthesis trials.

Authors:  Yu Xia; Qiushi Ren
Journal:  Sci Eng Ethics       Date:  2012-06-23       Impact factor: 3.525

7.  Subretinal electrode implantation in the P23H rat for chronic stimulations.

Authors:  J Salzmann; O P Linderholm; J-L Guyomard; M Paques; M Simonutti; M Lecchi; J Sommerhalder; E Dubus; M Pelizzone; D Bertrand; J Sahel; P Renaud; A B Safran; S Picaud
Journal:  Br J Ophthalmol       Date:  2006-06-05       Impact factor: 4.638

Review 8.  [Status of the subretinal implant project. An overview].

Authors:  F Gekeler; E Zrenner
Journal:  Ophthalmologe       Date:  2005-10       Impact factor: 1.059

9.  Simulation of intra-orbital optic nerve electrical stimulation.

Authors:  M Oozeer; C Veraart; V Legat; J Delbeke
Journal:  Med Biol Eng Comput       Date:  2005-09       Impact factor: 2.602

10.  Subretinal implantation and testing of polyimide film electrodes in cats.

Authors:  Helmut G Sachs; Thomas Schanze; Marcus Wilms; Andreas Rentzos; Ursula Brunner; Florian Gekeler; Lutz Hesse
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-12-01       Impact factor: 3.117
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