Literature DB >> 9303417

Analysis of ahpC gene mutations in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis.

C L Kelley1, D A Rouse, S L Morris.   

Abstract

The ahpC genes of 57 clinical isolates and one in vitro mutant of Mycobacterium tuberculosis were evaluated by nucleotide sequence analyses. Although compensatory ahpC promoter mutations were identified in 8 catalase-negative, katG-defective strains, the ahpC genes of 25 catalase-positive, isoniazid-resistant isolates and 25 drug-sensitive strains were not altered.

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Year:  1997        PMID: 9303417      PMCID: PMC164068          DOI: 10.1128/AAC.41.9.2057

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  15 in total

1.  Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis.

Authors:  S Dhandayuthapani; Y Zhang; M H Mudd; V Deretic
Journal:  J Bacteriol       Date:  1996-06       Impact factor: 3.490

2.  Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis.

Authors:  D R Sherman; K Mdluli; M J Hickey; T M Arain; S L Morris; C E Barry; C K Stover
Journal:  Science       Date:  1996-06-14       Impact factor: 47.728

3.  Overexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosis.

Authors:  K Johnsson; W A Froland; P G Schultz
Journal:  J Biol Chem       Date:  1997-01-31       Impact factor: 5.157

4.  Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities.

Authors:  S Sreevatsan; X Pan; Y Zhang; V Deretic; J M Musser
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

5.  Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid.

Authors:  Y Zhang; S Dhandayuthapani; V Deretic
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-12       Impact factor: 11.205

6.  Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.

Authors:  B Heym; E Stavropoulos; N Honoré; P Domenech; B Saint-Joanis; T M Wilson; D M Collins; M J Colston; S T Cole
Journal:  Infect Immun       Date:  1997-04       Impact factor: 3.441

7.  Site-directed mutagenesis of the katG gene of Mycobacterium tuberculosis: effects on catalase-peroxidase activities and isoniazid resistance.

Authors:  D A Rouse; J A DeVito; Z Li; H Byer; S L Morris
Journal:  Mol Microbiol       Date:  1996-11       Impact factor: 3.501

8.  ahpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex.

Authors:  T M Wilson; D M Collins
Journal:  Mol Microbiol       Date:  1996-03       Impact factor: 3.501

9.  Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance.

Authors:  J M Musser; V Kapur; D L Williams; B N Kreiswirth; D van Soolingen; J D van Embden
Journal:  J Infect Dis       Date:  1996-01       Impact factor: 5.226

10.  Disparate responses to oxidative stress in saprophytic and pathogenic mycobacteria.

Authors:  D R Sherman; P J Sabo; M J Hickey; T M Arain; G G Mahairas; Y Yuan; C E Barry; C K Stover
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-03       Impact factor: 11.205

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  37 in total

1.  Contribution of kasA analysis to detection of isoniazid-resistant Mycobacterium tuberculosis in Singapore.

Authors:  A S Lee; I H Lim; L L Tang; A Telenti; S Y Wong
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

2.  High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996 to 2001.

Authors:  Igor Mokrousov; Olga Narvskaya; Tatiana Otten; Elena Limeschenko; Lidia Steklova; Boris Vyshnevskiy
Journal:  Antimicrob Agents Chemother       Date:  2002-05       Impact factor: 5.191

3.  Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries.

Authors:  Kanchan Ajbani; Shou-Yean Grace Lin; Camilla Rodrigues; Duylinh Nguyen; Francine Arroyo; Janice Kaping; Lynn Jackson; Richard S Garfein; Donald Catanzaro; Kathleen Eisenach; Thomas C Victor; Valeru Crudu; Maria Tarcela Gler; Nazir Ismail; Edward Desmond; Antonino Catanzaro; Timothy C Rodwell
Journal:  Antimicrob Agents Chemother       Date:  2014-11-03       Impact factor: 5.191

4.  Mutations in katG, inhA, and ahpC genes of Brazilian isoniazid-resistant isolates of Mycobacterium tuberculosis.

Authors:  Márcia Susana N Silva; Simone G Senna; Marta O Ribeiro; Andréia R M Valim; Maria Alice Telles; Afrânio Kritski; Glenn P Morlock; Robert C Cooksey; Arnaldo Zaha; Maria Lucia R Rossetti
Journal:  J Clin Microbiol       Date:  2003-09       Impact factor: 5.948

5.  Screening and characterization of mutations in isoniazid-resistant Mycobacterium tuberculosis isolates obtained in Brazil.

Authors:  Rosilene Fressatti Cardoso; Robert C Cooksey; Glenn P Morlock; Patricia Barco; Leticia Cecon; Francisco Forestiero; Clarice Q F Leite; Daisy N Sato; Maria de Lourdes Shikama; Elsa M Mamizuka; Rosario D C Hirata; Mario H Hirata
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

6.  Detection of mutations associated with isoniazid resistance in Mycobacterium tuberculosis isolates from China.

Authors:  Min Zhang; Jun Yue; Yan-Ping Yang; Hong-Mei Zhang; Jian-Qiang Lei; Rui-Liang Jin; Xue-Lian Zhang; Hong-Hai Wang
Journal:  J Clin Microbiol       Date:  2005-11       Impact factor: 5.948

7.  Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam.

Authors:  M Caws; Phan Minh Duy; Dau Quang Tho; Nguyen Thi Ngoc Lan; Dai Viet Hoa; Jeremy Farrar
Journal:  J Clin Microbiol       Date:  2006-07       Impact factor: 5.948

8.  Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens.

Authors:  Didi Bang; Ase Bengård Andersen; Vibeke Østergaard Thomsen
Journal:  J Clin Microbiol       Date:  2006-07       Impact factor: 5.948

9.  Genetic and phenotypic characterizations of drug-resistant Mycobacterium tuberculosis isolates in Cheonan, Korea.

Authors:  Jae-Sik Jeon; Jae Kyung Kim; Qute Choi; Jong Wan Kim
Journal:  J Clin Lab Anal       Date:  2018-02-03       Impact factor: 2.352

10.  Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.

Authors:  Tao Luo; Ming Zhao; Xia Li; Peng Xu; Xiaohong Gui; Sam Pickerill; Kathryn DeRiemer; Jian Mei; Qian Gao
Journal:  Antimicrob Agents Chemother       Date:  2009-12-14       Impact factor: 5.191

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