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Literature DB >> 9232781

Canine tumour suppressor gene p53--mutation in a case of adenoma of circumanal glands.

B Mayr¹, W Schaffner, I Botto, M Reifinger, G Loupal.

Abstract

Highly conserved regions of the tumour suppressor gene p53, including the typical human tumour hot spots (codons 175, 245, 248, 249, 273 and 282), were investigated in various canine neoplasms. A mutation CGG-->TGG (arginine-->tryptophan) was detected in codon 249 in an adenoma of the circumanal gland.

Entities: Chemical Disease Gene Species

Mesh：

Year: 1997 PMID： 9232781 DOI： 10.1023/a:1005820607258

Source DB: PubMed Journal: Vet Res Commun ISSN： 0165-7380 Impact factor: 2.459

7 in total

1. An efficient salt-chloroform extraction of DNA from blood and tissues.

Authors: R Müllenbach; P J Lagoda; C Welter
Journal: Trends Genet Date: 1989-12 Impact factor: 11.639

Review 2. p53 mutations, another breast cancer prognostic factor.

Authors: R Callahan
Journal: J Natl Cancer Inst Date: 1992-06-03 Impact factor: 13.506

Review 3. Structural aspects of the p53 protein in relation to gene evolution.

Authors: T Soussi; C Caron de Fromentel; P May
Journal: Oncogene Date: 1990-07 Impact factor: 9.867

Review 4. The p53 tumour suppressor gene.

Authors: A J Levine; J Momand; C A Finlay
Journal: Nature Date: 1991-06-06 Impact factor: 49.962

5. Sequence of an exon of the canine p53 gene--mutation in a papilloma.

Authors: B Mayr; K Schellander; W Schleger; M Reifinger
Journal: Br Vet J Date: 1994 Jan-Feb

6. The canine p53 gene is subject to somatic mutations in thypoid carcinoma.

Authors: P Devilee; I S Van Leeuwen; A Voesten; G R Rutteman; J H Vos; C J Cornelisse
Journal: Anticancer Res Date: 1994 Sep-Oct Impact factor: 2.480

Review 7. The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

Authors: A J Levine; M E Perry; A Chang; A Silver; D Dittmer; M Wu; D Welsh
Journal: Br J Cancer Date: 1994-03 Impact factor: 7.640

7 in total

4 in total

Canine tumour suppressor gene p53--mutation in a case of adenoma of circumanal glands.

1. An efficient salt-chloroform extraction of DNA from blood and tissues.

Review 2. p53 mutations, another breast cancer prognostic factor.

Review 3. Structural aspects of the p53 protein in relation to gene evolution.

Review 4. The p53 tumour suppressor gene.

5. Sequence of an exon of the canine p53 gene--mutation in a papilloma.

6. The canine p53 gene is subject to somatic mutations in thypoid carcinoma.

Review 7. The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

1. Novel canine tumour suppressor gene p53 mutations in cases of skin and mammary neoplasms.

2. Identification of tumour-associated and germ line p53 mutations in canine mammary cancer.

3. Mutation of p53 Gene and Its Correlation with the Clinical Outcome in Dogs with Lymphoma.

4. Mutations of p53 Gene in Canine Sweat Gland Carcinomas Probably Associated with UV Radiation.