Literature DB >> 9232020

Some properties of the hazard function of the two-mutation clonal expansion model.

W F Heidenreich1, E G Luebeck, S H Moolgavkar.   

Abstract

We discuss the hazard function of the two-mutation clonal expansion model with time-dependent parameters, with particular emphasis on identifiability of the parameters. We explicitly construct identifiable parameter combinations, and illustrate the properties of the hazard function under perturbations of the underlying biological parameters.

Mesh:

Year:  1997        PMID: 9232020     DOI: 10.1111/j.1539-6924.1997.tb00878.x

Source DB:  PubMed          Journal:  Risk Anal        ISSN: 0272-4332            Impact factor:   4.000


  40 in total

1.  Genetic background and 227Thorium as risk factors in biologically based models for induction of bone cancer in mice.

Authors:  W F Heidenreich; M Rosemann
Journal:  Radiat Environ Biophys       Date:  2012-03-31       Impact factor: 1.925

2.  Breast cancer risk in atomic bomb survivors from multi-model inference with incidence data 1958-1998.

Authors:  J C Kaiser; P Jacob; R Meckbach; H M Cullings
Journal:  Radiat Environ Biophys       Date:  2011-09-23       Impact factor: 1.925

3.  Lung cancer mortality in the European uranium miners cohorts analyzed with a biologically based model taking into account radon measurement error.

Authors:  W F Heidenreich; L Tomasek; B Grosche; K Leuraud; D Laurier
Journal:  Radiat Environ Biophys       Date:  2012-05-24       Impact factor: 1.925

4.  Comparison of mortality and incidence solid cancer risk after radiation exposure in the Techa River Cohort.

Authors:  M Eidemüller; E Ostroumova; L Krestinina; S Epiphanova; A Akleyev; P Jacob
Journal:  Radiat Environ Biophys       Date:  2010-05-12       Impact factor: 1.925

5.  Studies of radon-exposed miner cohorts using a biologically based model: comparison of current Czech and French data with historic data from China and Colorado.

Authors:  W F Heidenreich; L Tomásek; A Rogel; D Laurier; M Tirmarche
Journal:  Radiat Environ Biophys       Date:  2004-11-30       Impact factor: 1.925

6.  Age-specific incidence of cancer: Phases, transitions, and biological implications.

Authors:  Rafael Meza; Jihyoun Jeon; Suresh H Moolgavkar; E Georg Luebeck
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-20       Impact factor: 11.205

7.  Modeling of cell inactivation and carcinogenesis in the atomic bomb survivors with applications to the mortality from all solid, stomach and liver cancer.

Authors:  Peter Jacob; Linda Walsh; Markus Eidemüller
Journal:  Radiat Environ Biophys       Date:  2008-05-15       Impact factor: 1.925

8.  Evaluation of screening strategies for pre-malignant lesions using a biomathematical approach.

Authors:  Jihyoun Jeon; Rafael Meza; Suresh H Moolgavkar; E Georg Luebeck
Journal:  Math Biosci       Date:  2008-02-26       Impact factor: 2.144

9.  A confidence building exercise in data and identifiability: Modeling cancer chemotherapy as a case study.

Authors:  Marisa C Eisenberg; Harsh V Jain
Journal:  J Theor Biol       Date:  2017-07-19       Impact factor: 2.691

10.  Should Never-Smokers at Increased Risk for Lung Cancer Be Screened?

Authors:  Kevin Ten Haaf; Harry J de Koning
Journal:  J Thorac Oncol       Date:  2015-09       Impact factor: 15.609

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