Literature DB >> 9203092

Inositol treatment of autism.

J Levine1, A Aviram, A Holan, A Ring, Y Barak, R H Belmaker.   

Abstract

Recent studies suggest that serotonin reuptake inhibitors are helpful in at least some symptoms of autism. Inositol is a precursor of the second messenger for some serotonin receptors, and has been reported effective in depression, panic disorder and obsessive-compulsive disorder. However a controlled double-blind crossover trial of inositol 200 mg/kg per day showed no benefit on 9 children with autism. Since biochemical studies could evaluate inositol in children already receiving serotonin reuptake inhibitors.

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Year:  1997        PMID： 9203092     DOI： 10.1007/BF01273191

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  11 in total

1.  Fluoxetine treatment of children and adults with autistic disorder and mental retardation.

Authors:  E H Cook; R Rowlett; C Jaselskis; B L Leventhal
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1992-07       Impact factor: 8.829

2.  A teacher rating scale for use in drug studies with children.

Authors:  C K Conners
Journal:  Am J Psychiatry       Date:  1969-12       Impact factor: 18.112

3.  Inositol treatment of obsessive-compulsive disorder.

Authors:  M Fux; J Levine; A Aviv; R H Belmaker
Journal:  Am J Psychiatry       Date:  1996-09       Impact factor: 18.112

Review 4.  Dietary influences on neurotransmission.

Authors:  S H Zeisel
Journal:  Adv Pediatr       Date:  1986

5.  Inositol supplementation in premature infants with respiratory distress syndrome.

Authors:  M Hallman; K Bry; K Hoppu; M Lappi; M Pohjavuori
Journal:  N Engl J Med       Date:  1992-05-07       Impact factor: 91.245

6.  Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS).

Authors:  E Schopler; R J Reichler; R F DeVellis; K Daly
Journal:  J Autism Dev Disord       Date:  1980-03

7.  Clomipramine treatment of stereotypic behaviors and self-injury in patients with developmental disabilities.

Authors:  H J Garber; J J McGonigle; G T Slomka; E Monteverde
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1992-11       Impact factor: 8.829

8.  Double-blind, controlled trial of inositol treatment of depression.

Authors:  J Levine; Y Barak; M Gonzalves; H Szor; A Elizur; O Kofman; R H Belmaker
Journal:  Am J Psychiatry       Date:  1995-05       Impact factor: 18.112

9.  Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder.

Authors:  J Benjamin; J Levine; M Fux; A Aviv; D Levy; R H Belmaker
Journal:  Am J Psychiatry       Date:  1995-07       Impact factor: 18.112

10.  Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization.

Authors:  S Rahman; R S Neuman
Journal:  Brain Res       Date:  1993-12-24       Impact factor: 3.252
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  4 in total

1.  Association of Myoinositol Transporters with Schizophrenia and Bipolar Disorder: Evidence from Human and Animal Studies.

Authors:  Marquis P Vawter; Abdul Rezzak Hamzeh; Edgar Muradyan; Olivier Civelli; Geoffrey W Abbott; Amal Alachkar
Journal:  Mol Neuropsychiatry       Date:  2019-08-08

2.  Single photon emission computed tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol.

Authors:  P D Carey; J Warwick; B H Harvey; D J Stein; S Seedat
Journal:  Metab Brain Dis       Date:  2004-06       Impact factor: 3.584

3.  Inositol for the prevention of neural tube defects: a pilot randomised controlled trial.

Authors:  Nicholas D E Greene; Kit-Yi Leung; Victoria Gay; Katie Burren; Kevin Mills; Lyn S Chitty; Andrew J Copp
Journal:  Br J Nutr       Date:  2016-02-05       Impact factor: 3.718

4.  Hippocampal Metabolite Profiles in Two Rat Models of Autism: NMR-Based Metabolomics Studies.

Authors:  B Toczylowska; E Zieminska; P Senator; J W Lazarewicz
Journal:  Mol Neurobiol       Date:  2020-05-28       Impact factor: 5.590
  4 in total

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