Literature DB >> 9188638

Genetic analysis of interactions between Gag proteins of Rous sarcoma virus.

X Li1, B Yuan, S P Goff.   

Abstract

The yeast two-hybrid system was used to characterize homomeric interactions between the Gag proteins of Rous sarcoma virus (RSV). The RSV Gag precursor was found to interact strongly with itself and not with various control proteins. The RSV Gag did not interact significantly with Gag proteins of a variety of other retroviruses, including murine leukemia viruses and primate lentiviruses. Deletion analysis suggested that two nonoverlapping regions are independently sufficient to mediate RSV Gag-Gag dimerization. One such region lies near the N terminus and contains p2, p10, and a large N-terminal part of the capsid (CA) domain; the other is localized in the C terminus and includes a small C-terminal portion of CA and the nucleocapsid protein. These interaction domains may play roles in viral assembly.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9188638      PMCID： PMC191806          DOI： 10.1128/JVI.71.7.5624-5630.1997

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  37 in total

1.  Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.

Authors:  G J Hannon; D Demetrick; D Beach
Journal:  Genes Dev       Date:  1993-12       Impact factor: 11.361

Review 2.  The yeast two-hybrid system for studying protein-protein interactions.

Authors:  J Luban; S P Goff
Journal:  Curr Opin Biotechnol       Date:  1995-02       Impact factor: 9.740

3.  An assembly domain of the Rous sarcoma virus Gag protein required late in budding.

Authors:  J W Wills; C E Cameron; C B Wilson; Y Xiang; R P Bennett; J Leis
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

4.  Specificity and sequence requirements for interactions between various retroviral Gag proteins.

Authors:  E K Franke; H E Yuan; K L Bossolt; S P Goff; J Luban
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

Review 5.  The two-hybrid system: an assay for protein-protein interactions.

Authors:  S Fields; R Sternglanz
Journal:  Trends Genet       Date:  1994-08       Impact factor: 11.639

6.  Characterization of a small (25-kilodalton) derivative of the Rous sarcoma virus Gag protein competent for particle release.

Authors:  R A Weldon; J W Wills
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

7.  Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein.

Authors:  R C Craven; A E Leure-duPree; R A Weldon; J W Wills
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

8.  Functional chimeras of the Rous sarcoma virus and human immunodeficiency virus gag proteins.

Authors:  R P Bennett; T D Nelle; J W Wills
Journal:  J Virol       Date:  1993-11       Impact factor: 5.103

9.  Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.

Authors:  A S Reicin; S Paik; R D Berkowitz; J Luban; I Lowy; S P Goff
Journal:  J Virol       Date:  1995-02       Impact factor: 5.103

10.  Positionally independent and exchangeable late budding functions of the Rous sarcoma virus and human immunodeficiency virus Gag proteins.

Authors:  L J Parent; R P Bennett; R C Craven; T D Nelle; N K Krishna; J B Bowzard; C B Wilson; B A Puffer; R C Montelaro; J W Wills
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103
View more
  8 in total

1.  Basic residues of the retroviral nucleocapsid play different roles in gag-gag and Gag-Psi RNA interactions.

Authors:  Eun-Gyung Lee; Maxine L Linial
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

2.  Intermolecular interactions between retroviral Gag proteins in the nucleus.

Authors:  Scott P Kenney; Timothy L Lochmann; Cullen L Schmid; Leslie J Parent
Journal:  J Virol       Date:  2007-10-31       Impact factor: 5.103

3.  The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production.

Authors:  Fadila Bouamr; Brian R Houck-Loomis; Martha De Los Santos; Rebecca J Casaday; Marc C Johnson; Stephen P Goff
Journal:  J Virol       Date:  2006-12-20       Impact factor: 5.103

4.  Cellular motor protein KIF-4 associates with retroviral Gag.

Authors:  Y Tang; U Winkler; E O Freed; T A Torrey; W Kim; H Li; S P Goff; H C Morse
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

5.  Analysis of Mason-Pfizer monkey virus Gag domains required for capsid assembly in bacteria: role of the N-terminal proline residue of CA in directing particle shape.

Authors:  M Rumlova-Klikova; E Hunter; M V Nermut; I Pichova; T Ruml
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

6.  The carboxy-terminal fragment of nucleolin interacts with the nucleocapsid domain of retroviral gag proteins and inhibits virion assembly.

Authors:  E Bacharach; J Gonsky; K Alin; M Orlova; S P Goff
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

7.  Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein.

Authors:  M T Burniston; A Cimarelli; J Colgan; S P Curtis; J Luban
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

8.  Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production.

Authors:  Margaret Q Wang; Wankee Kim; Guangxia Gao; Ted A Torrey; Herbert C Morse; Pietro De Camilli; Stephen P Goff
Journal:  J Biol       Date:  2003-12-04
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.