Literature DB >> 9140234

An analytical study, anti-inflammatory and analgesic effects of Harpagophytum procumbens and Harpagophytum zeyheri.

B Baghdikian1, M C Lanhers, J Fleurentin, E Ollivier, C Maillard, G Balansard, F Mortier.   

Abstract

The iridoids of Harpagophytum procumbens and Harpagophytum zeyheri were studied by CLHP. Harpagoside is the main iridoid for both drugs whereas 8-p-coumaroylharpagide is a representative iridoid of Harpagophytum zeyheri only. The ratio harpagoside/8-p-coumaroylharpagide can be used to distinguish chemically both species. For commercial dried aqueous extracts this ratio is intermediate because they are probably prepared from a mixture of H. procumbens and H. zeyheri drugs. The aqueous extracts of both drugs show similar analgesic and anti-inflammatory properties. Harpagophytum procumbens and Harpagophytum zeyheri should be accepted as sources for the drug Harpagophyti radix.

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Year:  1997        PMID: 9140234     DOI: 10.1055/s-2006-957638

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  9 in total

1.  Occurrence of iridoid glycosides in in vitro cultures and intact plants of Scrophularia nodosa L.

Authors:  Katja Sesterhenn; Melanie Distl; Michael Wink
Journal:  Plant Cell Rep       Date:  2006-09-14       Impact factor: 4.570

2.  Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytes.

Authors:  Abdul Haseeb; Mohammad Yunus Ansari; Tariq M Haqqi
Journal:  J Orthop Res       Date:  2016-05-04       Impact factor: 3.494

3.  Inhibitory effects of devil's claw (secondary root of Harpagophytum procumbens) extract and harpagoside on cytokine production in mouse macrophages.

Authors:  Kazunori Inaba; Kazuya Murata; Shunsuke Naruto; Hideaki Matsuda
Journal:  J Nat Med       Date:  2010-02-23       Impact factor: 2.343

4.  Iridoid and phenylethanoid/phenylpropanoid metabolite profiles of Scrophularia and Verbascum species used medicinally in North America.

Authors:  Korey J Brownstein; Mahmoud Gargouri; William R Folk; David R Gang
Journal:  Metabolomics       Date:  2017-10-03       Impact factor: 4.290

Review 5.  'Natural remedies' in the treatment of osteoarthritis.

Authors:  Karen Walker-Bone
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

6.  Anatomical study of secondary tuberized roots of Harpagophytum procumbens DC and quantification of harpagoside by high-performance liquid chromatography method.

Authors:  Fatiha El Babili; I Fouraste; C Rougaignon; C Moulis; C Chatelain
Journal:  Pharmacogn Mag       Date:  2012-04       Impact factor: 1.085

7.  Infrared-assisted extraction followed by high performance liquid chromatography to determine angoroside C, cinnamic acid, and harpagoside content in Scrophularia ningpoensis.

Authors:  Lina Su; Yinghui Deng; Nianzu Chen; Xiuwen Zhang; Taomin Huang
Journal:  BMC Complement Altern Med       Date:  2019-06-14       Impact factor: 3.659

8.  In vitro antioxidant activity of crude extracts of Harpagophytum zeyheri and their anti-inflammatory and cytotoxicity activity compared with diclofenac.

Authors:  Sibonokuhle F Ncube; Lyndy J McGaw; Emmanuel Mfotie Njoya; Hilton G T Ndagurwa; Peter J Mundy; Samson Sibanda
Journal:  BMC Complement Med Ther       Date:  2021-09-23

9.  Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum).

Authors:  Mbaki Muzila; Kimmo Rumpunen; Helen Wright; Helen Roberts; Melissa Grant; Hilde Nybom; Jasna Sehic; Anders Ekholm; Cecilia Widén
Journal:  Oxid Med Cell Longev       Date:  2016-06-27       Impact factor: 6.543

  9 in total

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