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Literature DB >> 9138573

Theoretical considerations on myofibril stiffness.

Abstract

A discrete model of the interaction between individual myofilaments was developed to study the stiffness of a sarcomere for the case in which filament compliance is not negligible. Our model retains, in the limit, the characteristics of the previously published model by Ford et al. (Ford, L. E., A. F. Huxley, and R. M. Simmons. 1981. The relation between stiffness and filament overlap in stimulated frog muscle fibres. J. Physiol. 311:219-249). In addition, the model is able to model the interaction in cases in which few cross-bridges are attached, or when the distribution of attached cross-bridges is not uniform. Our results confirm previous indications that it might be impossible to calculate the number of attached cross-bridges by using only stiffness measurements in quick-stretch (or release) experiments.

Mesh：

Substances：
Actins
Myosins

Year: 1997 PMID： 9138573 PMCID： PMC1184510 DOI： 10.1016/S0006-3495(97)78774-5

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

9 in total

1. Muscle structure and theories of contraction.

Authors: A F HUXLEY
Journal: Prog Biophys Biophys Chem Date: 1957

2. Actin compliance: are you pulling my chain?

Authors: Y E Goldman; A F Huxley
Journal: Biophys J Date: 1994-12 Impact factor: 4.033

3. X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle.

Authors: H E Huxley; A Stewart; H Sosa; T Irving
Journal: Biophys J Date: 1994-12 Impact factor: 4.033

4. Unbinding force of a single motor molecule of muscle measured using optical tweezers.

Authors: T Nishizaka; H Miyata; H Yoshikawa; S Ishiwata; K Kinosita
Journal: Nature Date: 1995-09-21 Impact factor: 49.962

5. Proposed mechanism of force generation in striated muscle.

Authors: A F Huxley; R M Simmons
Journal: Nature Date: 1971-10-22 Impact factor: 49.962

6. X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction.

Authors: K Wakabayashi; Y Sugimoto; H Tanaka; Y Ueno; Y Takezawa; Y Amemiya
Journal: Biophys J Date: 1994-12 Impact factor: 4.033

7. Compliance of thin filaments in skinned fibers of rabbit skeletal muscle.

Authors: H Higuchi; T Yanagida; Y E Goldman
Journal: Biophys J Date: 1995-09 Impact factor: 4.033

8. Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation.

Authors: H Kojima; A Ishijima; T Yanagida
Journal: Proc Natl Acad Sci U S A Date: 1994-12-20 Impact factor: 11.205

9. The relation between stiffness and filament overlap in stimulated frog muscle fibres.

Authors: L E Ford; A F Huxley; R M Simmons
Journal: J Physiol Date: 1981-02 Impact factor: 5.182

9 in total

7 in total

Theoretical considerations on myofibril stiffness.

1. Muscle structure and theories of contraction.

2. Actin compliance: are you pulling my chain?

3. X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle.

4. Unbinding force of a single motor molecule of muscle measured using optical tweezers.

5. Proposed mechanism of force generation in striated muscle.

6. X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction.

7. Compliance of thin filaments in skinned fibers of rabbit skeletal muscle.

8. Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation.

9. The relation between stiffness and filament overlap in stimulated frog muscle fibres.

1. Significant impact on muscle mechanics of small nonlinearities in myofilament elasticity.

2. Is the cross-bridge stiffness proportional to tension during muscle fiber activation?

3. Multi-scale modelling and the IUPS physiome project.

4. Characterization of actomyosin bond properties in intact skeletal muscle by force spectroscopy.

5. Crossbridge properties investigated by fast ramp stretching of activated frog muscle fibres.

Review 6. Crossbridge and filament compliance in muscle: implications for tension generation and lever arm swing.

7. Sarcomere tension-stiffness relation during the tetanus rise in single frog muscle fibres.