Literature DB >> 907995

Bioassay program for carcinogenic hazards of cancer chemotherapeutic agents.

E K Weisburger.   

Abstract

Various compounds and combinations thereof, of promise in the treatment of neoplastic diseases, were tested for possible carcinogenicity in Swiss mice and Sprague-Dawley rats. Some of the compounds were fairly active carcinogens, while others showed little or no evidence of carcinogenicity. The carcinogenicity of the drug combinations was generally less than that of the individual components.

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Year:  1977        PMID： 907995     DOI： 10.1002/1097-0142(197710)40:4+<1935::aid-cncr2820400827>3.0.co;2-r

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  11 in total

Review 1.  Mutagenic effects of some anticancer antibiotics.

Authors:  B K Vig
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

2.  Myelosuppression in polycythemia vera: chemotherapy or radiotherapy?

Authors:  Y Najean; C Dresch
Journal:  Blut       Date:  1982-01

3.  Incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and mutagenesis of herpes simplex virus type 1.

Authors:  G J Bubley; C S Crumpacker; L E Schnipper
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

4.  Effect of 5-fluorouracil on gastrointestinal carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

Authors:  Y Seto; H Nagawa; M Mori; T Tsuruo; T Muto
Journal:  Dig Dis Sci       Date:  1999-01       Impact factor: 3.199

5.  The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse.

Authors:  Gemma Molyneux; Frances M Gibson; Christabelle M Chen; Harpal K Marway; Sean McKeag; Charles V J Mifsud; Andrew M Pilling; Matthew J Whayman; John A Turton
Journal:  Int J Exp Pathol       Date:  2008-04       Impact factor: 1.925

6.  Persistence of chromosome rearrangements in peripheral lymphocytes from patients treated with melphalan for ovarian carcinoma.

Authors:  B Lambert; K Holmberg; N Einhorn
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

7.  Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice.

Authors:  H S Zackheim; E A Smuckler
Journal:  Experientia       Date:  1980-10-15

Review 8.  The role of transgenic mouse models in carcinogen identification.

Authors:  John B Pritchard; John E French; Barbara J Davis; Joseph K Haseman
Journal:  Environ Health Perspect       Date:  2003-04       Impact factor: 9.031

Review 9.  Chemical carcinogenesis studies in nonhuman primates.

Authors:  Shozo Takayama; Unnur P Thorgeirsson; Richard H Adamson
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2008       Impact factor: 3.493

10.  Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas.

Authors:  W J Bodell; T Aida; M S Berger; M L Rosenblum
Journal:  Environ Health Perspect       Date:  1985-10       Impact factor: 9.031
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