| Literature DB >> 907326 |
B K Lee, J V Bailey, R G Condon, J A Marquez, G H Wagman, M J Weinstein.
Abstract
Sisomicin was transformed to gentamicin C(2b) by Micromonospora rhodorangea NRRL 5326. The mechanisms involved in the biotransformation are the 6'-N-methylation and the (4'-5')-reduction. The progression of the methylation was followed by the isotope technique, but the reduction reaction was not monitored.Entities:
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Year: 1977 PMID： 907326 PMCID： PMC429914 DOI： 10.1128/AAC.12.3.335
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191