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Literature DB >> 9061615

Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans.

Abstract

A cDNA encoding a serotonin receptor has been isolated from a Caenorhabditis elegans mixed stage cDNA library. The nematode serotonin receptor, designated 5HT-Ce, was permanently expressed in murine Ltk-cells, where it mediates adenylate cyclase attenuation. Sequence analysis and the pharmacological profiles demonstrate its relatedness not only to Drosophila and Lymnae 5HT receptors but also to mammalian 5HT1a receptors. The 5HT-Ce-gene does not map close to the position of any known serotonergic mutations.

Entities: Gene Species

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Year: 1997 PMID： 9061615 DOI： 10.1007/BF02736863

Source DB: PubMed Journal: J Mol Neurosci ISSN： 0895-8696 Impact factor: 3.444

43 in total

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Journal: Proc Natl Acad Sci U S A Date: 1992-06-15 Impact factor: 11.205

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Authors: P Witz; N Amlaiky; J L Plassat; L Maroteaux; E Borrelli; R Hen
Journal: Proc Natl Acad Sci U S A Date: 1990-11 Impact factor: 11.205

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Journal: Proc Natl Acad Sci U S A Date: 1993-01-01 Impact factor: 11.205

8. A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation.

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Journal: Nat Genet Date: 1992-05 Impact factor: 38.330

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Authors: F Saudou; U Boschert; N Amlaiky; J L Plassat; R Hen
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35 in total

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Authors: Robert J Hobson; Vera M Hapiak; Hong Xiao; Kara L Buehrer; Patricia R Komuniecki; Richard W Komuniecki
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5. Characterization of the 5-HT1A receptor of the honeybee (Apis mellifera) and involvement of serotonin in phototactic behavior.

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Review 6. Neurotransmitter signaling through heterotrimeric G proteins: insights from studies in C. elegans.

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Journal: WormBook Date: 2018-12-11

Review 7. Monoaminergic signaling as a target for anthelmintic drug discovery: receptor conservation among the free-living and parasitic nematodes.

Authors: Richard Komuniecki; Wen Jing Law; Aaron Jex; Peter Geldhof; John Gray; Bruce Bamber; Robin B Gasser
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8. Dopamine counteracts octopamine signalling in a neural circuit mediating food response in C. elegans.

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9. LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system.

Authors: Ephraim L Tsalik; Timothy Niacaris; Adam S Wenick; Kelvin Pau; Leon Avery; Oliver Hobert
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10. Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.

Authors: Marishka K Brown; Yuan Luo
Journal: BMC Neurosci Date: 2009-06-22 Impact factor: 3.288