Literature DB >> 9029798

Estimating the age of the common ancestor of a sample of DNA sequences.

Y X Fu1, W H Li.   

Abstract

We present a simple Monte Carlo method for estimating the age of the most recent common ancestor (MRCA) of a sample of DNA sequences. We show that Templeton's (1993) estimator of the age of the MRCA based on the maximum number of nucleotide differences between two sequences in a sample is inaccurate, and we demonstrate the new method by reanalyzing a sample of DNA sequences from human Y chromosomes and a sample of human Alu sequences.

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Year:  1997        PMID： 9029798     DOI： 10.1093/oxfordjournals.molbev.a025753

Source DB:  PubMed          Journal:  Mol Biol Evol        ISSN： 0737-4038            Impact factor:   16.240


  24 in total

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