Literature DB >> 14631095

A comparison of two popular statistical methods for estimating the time to most recent common ancestor (TMRCA) from a sample of DNA sequences.

Analabha Basu1, Partha P Majumder.   

Abstract

We have compared two statistical methods of estimating the time to most recent common ancestor (TMRCA) from a sample of DNA sequences, which have been proposed by Templeton (1993) and Bandelt et al. (1995). Monte-Carlo simulations were used for generating DNA sequence data. Different evolutionary scenarios were simulated and the estimation procedures were evaluated. We have found that for both methods (i) the estimates are insensitive to demographic parameters and (ii) the standard deviations of the estimates are too high for these methods to be reliably used in practice.

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Year:  2003        PMID： 14631095     DOI： 10.1007/bf02715874

Source DB:  PubMed          Journal:  J Genet        ISSN： 0022-1333            Impact factor:   1.166


  7 in total

1.  mtDNA variation among Greenland Eskimos: the edge of the Beringian expansion.

Authors:  J Saillard; P Forster; N Lynnerup; H J Bandelt; S Nørby
Journal:  Am J Hum Genet       Date:  2000-08-02       Impact factor: 11.025

2.  Mitochondrial portraits of human populations using median networks.

Authors:  H J Bandelt; P Forster; B C Sykes; M B Richards
Journal:  Genetics       Date:  1995-10       Impact factor: 4.562

3.  Estimating the age of the common ancestor of a sample of DNA sequences.

Authors:  Y X Fu; W H Li
Journal:  Mol Biol Evol       Date:  1997-02       Impact factor: 16.240

4.  Inferring coalescence times from DNA sequence data.

Authors:  S Tavaré; D J Balding; R C Griffiths; P Donnelly
Journal:  Genetics       Date:  1997-02       Impact factor: 4.562

5.  Demographic history of India and mtDNA-sequence diversity.

Authors:  J L Mountain; J M Hebert; S Bhattacharyya; P A Underhill; C Ottolenghi; M Gadgil; L L Cavalli-Sforza
Journal:  Am J Hum Genet       Date:  1995-04       Impact factor: 11.025

6.  Evolutionary relationship of DNA sequences in finite populations.

Authors:  F Tajima
Journal:  Genetics       Date:  1983-10       Impact factor: 4.562

7.  A recent common ancestry for human Y chromosomes.

Authors:  M F Hammer
Journal:  Nature       Date:  1995-11-23       Impact factor: 49.962
  7 in total
  2 in total

1.  Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps.

Authors:  Weihua Zhang; Andrew Collins; Jane Gibson; William J Tapper; Sarah Hunt; Panos Deloukas; David R Bentley; Newton E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-16       Impact factor: 11.205

2.  Testing for archaic hominin admixture on the X chromosome: model likelihoods for the modern human RRM2P4 region from summaries of genealogical topology under the structured coalescent.

Authors:  Murray P Cox; Fernando L Mendez; Tatiana M Karafet; Maya Metni Pilkington; Sarah B Kingan; Giovanni Destro-Bisol; Beverly I Strassmann; Michael F Hammer
Journal:  Genetics       Date:  2008-01       Impact factor: 4.562
  2 in total

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