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Literature DB >> 9021210

Transferable hyperproduction of TEM-1 beta-lactamase in Shigella flexneri due to a point mutation in the pribnow box.

L K Siu¹, P L Ho, K Y Yuen, S S Wong, P Y Chau.

Abstract

TEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the blaTEM gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G-->T transversion at position 1 of the -10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction.

Entities: Chemical Species

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Year: 1997 PMID： 9021210 PMCID： PMC163732

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

18 in total

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19 in total

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Authors: G Arlet; S Goussard; P Courvalin; A Philippon
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Journal: Antimicrob Agents Chemother Date: 2000-02 Impact factor: 5.191

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Journal: Antimicrob Agents Chemother Date: 2000-10 Impact factor: 5.191

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Journal: Antimicrob Agents Chemother Date: 1999-02 Impact factor: 5.191

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Journal: Antimicrob Agents Chemother Date: 1998-04 Impact factor: 5.191

10. Repeated occurrence of diverse extended-spectrum beta-lactamases in minor serotypes of food-borne Salmonella enterica subsp. enterica.

Authors: L Politi; P T Tassios; M Lambiri; A Kansouzidou; M Pasiotou; A C Vatopoulos; K Mellou; N J Legakis; L S Tzouvelekis
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