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Literature DB >> 9016523

p53 and APC gene mutations: software and databases.

Abstract

A large number of different mutations in the APC and p53 tumor suppressor genes have been identified in various types of cancer. This substantial increase since our previous reports can enable analyses which were not previously possible. In order to capture all these new data, the software permitting analysis has been improved. This report describes the various improvements since the second release of the database.

Entities: Disease Gene

Mesh：

Year: 1997 PMID： 9016523 PMCID： PMC146392 DOI： 10.1093/nar/25.1.138

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

7 in total

1. Software and database for the analysis of mutations in the human FBN1 gene.

Authors: G Collod; C Béroud; T Soussi; C Junien; C Boileau
Journal: Nucleic Acids Res Date: 1996-01-01 Impact factor: 16.971

2. p53 gene mutation: software and database.

Authors: C Béroud; F Verdier; T Soussi
Journal: Nucleic Acids Res Date: 1996-01-01 Impact factor: 16.971

3. APC gene: database of germline and somatic mutations in human tumors and cell lines.

Authors: C Béroud; T Soussi
Journal: Nucleic Acids Res Date: 1996-01-01 Impact factor: 16.971

4. APC mutations in colorectal tumors with mismatch repair deficiency.

Authors: J Huang; N Papadopoulos; A J McKinley; S M Farrington; L J Curtis; A H Wyllie; S Zheng; J K Willson; S D Markowitz; P Morin; K W Kinzler; B Vogelstein; M G Dunlop
Journal: Proc Natl Acad Sci U S A Date: 1996-08-20 Impact factor: 11.205

5. Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444.

Authors: R Caspari; S Olschwang; W Friedl; M Mandl; C Boisson; T Böker; A Augustin; M Kadmon; G Möslein; G Thomas
Journal: Hum Mol Genet Date: 1995-03 Impact factor: 6.150

6. Deletions and insertions in the p53 tumor suppressor gene in human cancers: confirmation of the DNA polymerase slippage/misalignment model.

Authors: M S Greenblatt; A P Grollman; C C Harris
Journal: Cancer Res Date: 1996-05-01 Impact factor: 12.701

7. Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene.

Authors: D R Davies; J G Armstrong; N Thakker; K Horner; S P Guy; T Clancy; P Sloan; V Blair; C Dodd; T W Warnes
Journal: Am J Hum Genet Date: 1995-11 Impact factor: 11.025

7 in total

5 in total

Review 1. Hypermutability in carcinogenesis.

Authors: B S Strauss
Journal: Genetics Date: 1998-04 Impact factor: 4.562

2. Combined molecular and clinical approaches for the identification of families with familial adenomatous polyposis coli.

Authors: J F Gebert; C Dupon; M Kadmon; M Hahn; C Herfarth; M von Knebel Doeberitz; H K Schackert
Journal: Ann Surg Date: 1999-03 Impact factor: 12.969