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Literature DB >> 900924

In vitro susceptibility studies with cefaclor and cephalexin.

W M Scheld, O M Korzeniowski, M A Sande.

Abstract

The in vitro activity of cefaclor and cephalexin against clinical isolates of four bacterial genera was compared. Both agents had a similar range of activity, but cefaclor was significantly more active by weight than cephalexin for most isolates tested.

Entities: Chemical

Mesh：

Substances：
Cephalosporins
Cephalexin

Year: 1977 PMID： 900924 PMCID： PMC429901 DOI： 10.1128/AAC.12.2.290

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

8 in total

Review 1. Drug therapy: The newer cephalosporins.

Authors: R C Moellering; M N Swartz
Journal: N Engl J Med Date: 1976-01-01 Impact factor: 91.245

2. Comparative pharmacology of cefaclor and cephalexin.

Authors: O M Korzeniowski; W M Scheld; M A Sande
Journal: Antimicrob Agents Chemother Date: 1977-08 Impact factor: 5.191

3. Comparison of in vitro activity of cephalexin, cephradine, and cefaclor.

Authors: N J Bill; J A Washington
Journal: Antimicrob Agents Chemother Date: 1977-03 Impact factor: 5.191

4. Clinical evaluation of cephradine, a new oral cephalosporin.

Authors: J F Scholand; G R Hodges; R J Fass; S Saslaw
Journal: Am J Med Sci Date: 1974-02 Impact factor: 2.378

5. Detailed methodology and implementation of a semiautomated serial dilution microtechnique for antimicrobial susceptibility testing.

Authors: J D MacLowry; M J Jaqua; S T Selepak
Journal: Appl Microbiol Date: 1970-07

6. Cephradine. Antibacterial activity and clinical effectiveness.

Authors: J Klastersky; D Daneau; D Weerts
Journal: Chemotherapy Date: 1973 Impact factor: 2.544

7. Estimating savings from hospital merger.

Authors: J R Boston; W R Casparis
Journal: Health Serv Res Date: 1972 Impact factor: 3.402

8. The in vitro spectrum of the cephalosporins.

Authors: J A Washington
Journal: Mayo Clin Proc Date: 1976-04 Impact factor: 7.616

8 in total

6 in total

In vitro susceptibility studies with cefaclor and cephalexin.

Review 1. Drug therapy: The newer cephalosporins.

2. Comparative pharmacology of cefaclor and cephalexin.

3. Comparison of in vitro activity of cephalexin, cephradine, and cefaclor.

4. Clinical evaluation of cephradine, a new oral cephalosporin.

5. Detailed methodology and implementation of a semiautomated serial dilution microtechnique for antimicrobial susceptibility testing.

6. Cephradine. Antibacterial activity and clinical effectiveness.

7. Estimating savings from hospital merger.

8. The in vitro spectrum of the cephalosporins.

1. Comparative pharmacology of cefaclor and cephalexin.

2. Concentration relationships of cefaclor in serum, interstitial fluid, bile, and urine of dogs.

3. Pharmacokinetics of cefaclor and cephalexin: dosage nomograms for impaired renal function.

4. Pharmacology of cefaclor in normal volunteers and patients with renal failure.

5. Cefadroxil in the treatment of susceptible infections in infants and children.

6. Pharmacological evaluation of cefaclor in volunteers.