Literature DB >> 8980780

Induction of DnaK and GroEL heat shock proteins by fluoroquinolones in Escherichia coli.

T Mizushima1, M Matsuo, K Sekimizu.   

Abstract

Various fluoroquinolones (norfloxacin, enoxacin, ofloxacin, levofloxacin, and sparfloxacin) induce DnaK and GroEL heat shock proteins in Escherichia coli. The induction is transient, consistent with the kinetics of cellular DNA relaxation. The concentrations of fluoroquinolones required for induction are similar to those required for DNA relaxation and much higher than those required for cell death.

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Year:  1997        PMID: 8980780      PMCID: PMC163685     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  30 in total

1.  Renaturation of denatured lambda repressor requires heat shock proteins.

Authors:  G A Gaitanaris; A G Papavassiliou; P Rubock; S J Silverstein; M E Gottesman
Journal:  Cell       Date:  1990-06-15       Impact factor: 41.582

2.  Mutations in the rpoH (htpR) gene of Escherichia coli K-12 phenotypically suppress a temperature-sensitive mutant defective in the sigma 70 subunit of RNA polymerase.

Authors:  A D Grossman; Y N Zhou; C Gross; J Heilig; G E Christie; R Calendar
Journal:  J Bacteriol       Date:  1985-03       Impact factor: 3.490

3.  Heat shock regulatory gene (htpR) of Escherichia coli is required for growth at high temperature but is dispensable at low temperature.

Authors:  T Yura; T Tobe; K Ito; T Osawa
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

4.  The htpR gene product of E. coli is a sigma factor for heat-shock promoters.

Authors:  A D Grossman; J W Erickson; C A Gross
Journal:  Cell       Date:  1984-09       Impact factor: 41.582

Review 5.  Linkage map of Escherichia coli K-12, edition 7.

Authors:  B J Bachmann
Journal:  Microbiol Rev       Date:  1983-06

Review 6.  The genetics and regulation of heat-shock proteins.

Authors:  F C Neidhardt; R A VanBogelen; V Vaughn
Journal:  Annu Rev Genet       Date:  1984       Impact factor: 16.830

7.  Positive regulatory gene for temperature-controlled proteins in Escherichia coli.

Authors:  F C Neidhardt; R A VanBogelen
Journal:  Biochem Biophys Res Commun       Date:  1981-05-29       Impact factor: 3.575

8.  Isolation and physical mapping of temperature-sensitive mutants defective in heat-shock induction of proteins in Escherichia coli.

Authors:  T Tobe; K Ito; T Yura
Journal:  Mol Gen Genet       Date:  1984

9.  Induction by psychotropic drugs and local anesthetics of DnaK and GroEL proteins in Escherichia coli.

Authors:  K Tanji; T Mizushima; S Natori; K Sekimizu
Journal:  Biochim Biophys Acta       Date:  1992-01-06

10.  DNA topoisomerase I mutants. Increased heterogeneity in linking number and other replicon-dependent changes in DNA supercoiling.

Authors:  G J Pruss
Journal:  J Mol Biol       Date:  1985-09-05       Impact factor: 5.469

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  3 in total

1.  Suppression of ethanol-induced apoptotic DNA fragmentation by geranylgeranylacetone in cultured guinea pig gastric mucosal cells.

Authors:  T Mizushima; S Tsutsumi; K Rokutan; T Tsuchiya
Journal:  Dig Dis Sci       Date:  1999-03       Impact factor: 3.199

2.  Prior antibacterial peptide-mediated inhibition of protein folding in bacteria mutes resistance enzymes.

Authors:  Laszlo Otvos; Vanessa de Olivier Inacio; John D Wade; Predrag Cudic
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

3.  Induction of fibronectin-binding proteins and increased adhesion of quinolone-resistant Staphylococcus aureus by subinhibitory levels of ciprofloxacin.

Authors:  C Bisognano; P Vaudaux; P Rohner; D P Lew; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

  3 in total

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