Literature DB >> 16940114

Prior antibacterial peptide-mediated inhibition of protein folding in bacteria mutes resistance enzymes.

Laszlo Otvos1, Vanessa de Olivier Inacio, John D Wade, Predrag Cudic.   

Abstract

The antimicrobial activity of amoxicillin against TEM-1-expressing strains could be fully recovered when bacteria were preincubated with sublethal doses of an antibacterial peptide derivative. Assays with the simultaneous administration of antibiotics or synergy assays with kanamycin or ciprofloxacin, where resistance development does not involve properly folded proteins, failed to yield similar results.

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Year:  2006        PMID： 16940114      PMCID： PMC1563543          DOI： 10.1128/AAC.00205-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

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Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

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Review 6.  A functional classification scheme for beta-lactamases and its correlation with molecular structure.

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7.  Kinetic and thermodynamic consequences of the removal of the Cys-77-Cys-123 disulphide bond for the folding of TEM-1 beta-lactamase.

Authors:  M Vanhove; G Guillaume; P Ledent; J H Richards; R H Pain; J M Frère
Journal:  Biochem J       Date:  1997-01-15       Impact factor: 3.857

Review 8.  beta-Lactamases in laboratory and clinical resistance.

Authors:  D M Livermore
Journal:  Clin Microbiol Rev       Date:  1995-10       Impact factor: 26.132

9.  In vitro and in vivo activity of an antibacterial peptide analog against uropathogens.

Authors:  Mare Cudic; C Virginia Lockatell; David E Johnson; Laszlo Otvos
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10.  Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin.

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2.  Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections.

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Journal:  J Antimicrob Chemother       Date:  2010-09-01       Impact factor: 5.790

3.  Intramuscularly administered peptide A3-APO is effective against carbapenem-resistant Acinetobacter baumannii in mouse models of systemic infections.

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Journal:  Biopolymers       Date:  2011       Impact factor: 2.505

4.  Effect of intracellular expression of antimicrobial peptide LL-37 on growth of escherichia coli strain TOP10 under aerobic and anaerobic conditions.

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Journal:  Antimicrob Agents Chemother       Date:  2013-07-15       Impact factor: 5.191

5.  Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo.

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6.  Influence of Substitutions in the Binding Motif of Proline-Rich Antimicrobial Peptide ARV-1502 on 70S Ribosome Binding and Antimicrobial Activity.

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Journal:  Int J Mol Sci       Date:  2022-03-15       Impact factor: 5.923
  6 in total

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