Literature DB >> 8940263

Individual variation in recombination among human males.

J Yu1, L Lazzeroni, J Qin, M M Huang, W Navidi, H Erlich, N Arnheim.   

Abstract

Studies of recombination between the markers D6S291 and D6S109 in individuals by sperm typing provide direct evidence for significant variation in recombination among humans. A statistically significant difference in the recombination fraction (range 5.1%-11.2%) was detected among five donors. This variation could reflect polymorphisms in genes affecting recombination or in chromosome structure. Ignoring this variability in studies designed to examine the relationship between physical and genetic distances could lead to incorrect inferences. Individual variation in recombination makes it difficult to predict the recombination fraction for an interval in any particular individual. This could be important in certain genetic counseling situations.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8940263      PMCID： PMC1914855     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  20 in total

1.  XY chromosome nondisjunction in man is associated with diminished recombination in the pseudoautosomal region.

Authors:  T J Hassold; S L Sherman; D Pettay; D C Page; P A Jacobs
Journal:  Am J Hum Genet       Date:  1991-08       Impact factor: 11.025

2.  Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16.

Authors:  R H Reeves; M R Crowley; B F O'Hara; J D Gearhart
Journal:  Genomics       Date:  1990-09       Impact factor: 5.736

3.  Recombination events suggest potential sites for the Huntington's disease gene.

Authors:  M E MacDonald; J L Haines; M Zimmer; S V Cheng; S Youngman; W L Whaley; N Wexler; M Bucan; B A Allitto; B Smith
Journal:  Neuron       Date:  1989-08       Impact factor: 17.173

4.  Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers.

Authors:  X F Cui; H H Li; T M Goradia; K Lange; H H Kazazian; D Galas; N Arnheim
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

5.  Amplification and analysis of DNA sequences in single human sperm and diploid cells.

Authors:  H H Li; U B Gyllensten; X F Cui; R K Saiki; H A Erlich; N Arnheim
Journal:  Nature       Date:  1988-09-29       Impact factor: 49.962

6.  A genetic linkage map of the human genome.

Authors:  H Donis-Keller; P Green; C Helms; S Cartinhour; B Weiffenbach; K Stephens; T P Keith; D W Bowden; D R Smith; E S Lander
Journal:  Cell       Date:  1987-10-23       Impact factor: 41.582

7.  Allelic specific heterogeneity in the Pi:Gm linkage group.

Authors:  L R Weitkamp; D Cox; S Guttormsen; E Johnston; S Hempfling
Journal:  Cytogenet Cell Genet       Date:  1978

8.  Further studies on bivalent chiasma frequency in human males with normal karyotypes.

Authors:  D A Laurie; M A Hultén
Journal:  Ann Hum Genet       Date:  1985-07       Impact factor: 1.670

9.  The Gm-Pi linkage in 843 French families: effect of the alleles Pi Z and Pi S.

Authors:  M C Babron; J Constans; J M Dugoujon; A Cambon-Thomsen; C Bonaïti-Pellié
Journal:  Ann Hum Genet       Date:  1990-05       Impact factor: 1.670

10.  A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates.

Authors:  K H Buetow; R Shiang; P Yang; Y Nakamura; G M Lathrop; R White; J J Wasmuth; S Wood; L D Berdahl; N J Leysens
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025
View more
  21 in total

1.  Characterization of human crossover interference.

Authors:  K W Broman; J L Weber
Journal:  Am J Hum Genet       Date:  2000-05-08       Impact factor: 11.025

2.  An enhanced linkage map of the sheep genome comprising more than 1000 loci.

Authors:  J F Maddox; K P Davies; A M Crawford; D J Hulme; D Vaiman; E P Cribiu; B A Freking; K J Beh; N E Cockett; N Kang; C D Riffkin; R Drinkwater; S S Moore; K G Dodds; J M Lumsden; T C van Stijn; S H Phua; D L Adelson; H R Burkin; J E Broom; J Buitkamp; L Cambridge; W T Cushwa; E Gerard; S M Galloway; B Harrison; R J Hawken; S Hiendleder; H M Henry; J F Medrano; K A Paterson; L Schibler; R T Stone; B van Hest
Journal:  Genome Res       Date:  2001-07       Impact factor: 9.043

3.  X chromosome effect on maternal recombination and meiotic drive in the mouse.

Authors:  Elena de La Casa-Esperón; J Concepción Loredo-Osti; Fernando Pardo-Manuel de Villena; Tammi L Briscoe; Jan Michel Malette; Joe E Vaughan; Kenneth Morgan; Carmen Sapienza
Journal:  Genetics       Date:  2002-08       Impact factor: 4.562

Review 4.  Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved.

Authors:  Norman Arnheim; Peter Calabrese; Magnus Nordborg
Journal:  Am J Hum Genet       Date:  2003-05-22       Impact factor: 11.025

5.  Recombination-associated sequence homogenization of neighboring Alu elements: signature of nonallelic gene conversion.

Authors:  Alexey Aleshin; Degui Zhi
Journal:  Mol Biol Evol       Date:  2010-05-07       Impact factor: 16.240

6.  Polymorphic variation in human meiotic recombination.

Authors:  Vivian G Cheung; Joshua T Burdick; Deborah Hirschmann; Michael Morley
Journal:  Am J Hum Genet       Date:  2007-01-23       Impact factor: 11.025

7.  High-resolution patterns of meiotic recombination across the human major histocompatibility complex.

Authors:  Michael Cullen; Stephen P Perfetto; William Klitz; George Nelson; Mary Carrington
Journal:  Am J Hum Genet       Date:  2002-09-23       Impact factor: 11.025

8.  Meiotic recombinations within major histocompatibility complex of human embryos.

Authors:  Fulya Taylan; Ender Altiok
Journal:  Immunogenetics       Date:  2012-08-15       Impact factor: 2.846

9.  Genetic analysis of meiotic recombination in humans by use of sperm typing: reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3.

Authors:  G M Brown; M Leversha; M Hulten; M A Ferguson-Smith; N A Affara; R A Furlong
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

10.  Variation in meiotic recombination frequencies among human males.

Authors:  Fei Sun; Kiril Trpkov; Alfred Rademaker; Evelyn Ko; Renée H Martin
Journal:  Hum Genet       Date:  2004-12-01       Impact factor: 4.132
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.