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Literature DB >> 891823

Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine.

Abstract

Human lymphocytes exposed to the effects of long wave UV radiation in the presence of 8-methoxypsoralen prior to stimulation by PHA show dose related sister chromatid exchanges after 2 replication cycles in vitro. This has implications for interpreting the processes involved and for monitoring DNA damaging agents in vivo.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1977 PMID： 891823 DOI： 10.1007/bf01945989

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

14 in total

1. The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities.

Authors: B Beek; G Obe
Journal: Humangenetik Date: 1975-09-10

2. EVIDENCES OF A PHOTOREACTION OF THE PHOTOSENSITIZING FUROCOUMARINS WITH DNA AND WITH PYRIMIDINE NUCLEOSIDES AND NUCLEOTIDES.

Authors: L MUSAJO; G RODIGHIERO; F DALLACQUA
Journal: Experientia Date: 1965-01-15

Review 3. Environmental mutagenesis and repair.

Authors: M S Legator; W G Flamm
Journal: Annu Rev Biochem Date: 1973 Impact factor: 23.643

4. Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.

Authors: J A Parrish; T B Fitzpatrick; L Tanenbaum; M A Pathak
Journal: N Engl J Med Date: 1974-12-05 Impact factor: 91.245

5. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors: S A Latt
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

6. Psoralen monoadducts and interstrand cross-links in DNA.

Authors: R S Cole
Journal: Biochim Biophys Acta Date: 1971-11-29

7. Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

Authors: P Perry; H J Evans
Journal: Nature Date: 1975-11-13 Impact factor: 49.962

8. Sister chromatid exchanges in lymphocytes of psoriatics after treatment with 8-methoxypsoralen and long wave ultraviolet radiation.

Authors: D Mourelatos; M J Faed; P W Gould; B E Johnson; W Frain-Bell
Journal: Br J Dermatol Date: 1977-12 Impact factor: 9.302

Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine.

1. The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities.

2. EVIDENCES OF A PHOTOREACTION OF THE PHOTOSENSITIZING FUROCOUMARINS WITH DNA AND WITH PYRIMIDINE NUCLEOSIDES AND NUCLEOTIDES.

Review 3. Environmental mutagenesis and repair.

4. Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.

5. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

6. Psoralen monoadducts and interstrand cross-links in DNA.

7. Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

8. Sister chromatid exchanges in lymphocytes of psoriatics after treatment with 8-methoxypsoralen and long wave ultraviolet radiation.

9. 8-methoxypsoralen and UVA promote sister-chromatid exchanges.

10. MITOMYCINS AND PORFIROMYCIN: CHEMICAL MECHANISM OF ACTIVATION AND CROSS-LINKING OF DNA.

1. Sister chromatid exchange in lymphocytes from patients with malignant lymphoma.

2. The effect of 8-methoxypsoralen and longwave UV-radiation on growth rates of human epidermal cells in culture.

3. Psoralen/UVA treatment and chromosomes. II. Analyses of psoriasis patients.