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Literature DB >> 8905441

MDMA induced hyperthermia: report of a fatality and review of current therapy.

Abstract

Ingestion of 3,4-methylene dioxymethamphetamine (MDMA), commonly known as "Ecstasy", can produce toxicity that is characterised by hyperthermia, coagulopathy, rhabdomyolysis and renal failure. We report a fatality associated with MDMA ingestion and briefly review the current literature on MDMA-induced hyperthermia.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1996 PMID： 8905441 DOI： 10.1007/bf02044131

Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440

13 in total

1. Another death from Ecstacy.

Authors: N T Campkin; U M Davies
Journal: J R Soc Med Date: 1992-01 Impact factor: 5.344

Review 2. The serotonin syndrome.

Authors: H Sternbach
Journal: Am J Psychiatry Date: 1991-06 Impact factor: 18.112

Review 3. Myocardial contraction bands revisited.

Authors: S B Karch; M E Billingham
Journal: Hum Pathol Date: 1986-01 Impact factor: 3.466

Review 4. Motor effects of serotonin in the central nervous system.

Authors: S C Gerson; R J Baldessarini
Journal: Life Sci Date: 1980-10-20 Impact factor: 5.037

5. Multiple severe complications from recreational ingestion of MDMA ('Ecstasy')

Authors: C Brown; J Osterloh
Journal: JAMA Date: 1987-08-14 Impact factor: 56.272

6. Survival following 'Ecstasy' ingestion with a peak temperature of 42 degrees C.

Authors: A S Logan; B Stickle; N O'Keefe; H Hewitson
Journal: Anaesthesia Date: 1993-11 Impact factor: 6.955

7. Ecstasy intoxication: appreciation of complications and the role of dantrolene.

Authors: C Webb; V Williams
Journal: Anaesthesia Date: 1993-06 Impact factor: 6.955

8. Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

Authors: J A Henry; K J Jeffreys; S Dawling
Journal: Lancet Date: 1992-08-15 Impact factor: 79.321

9. Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.

Authors: C J Schmidt; C K Black; G M Abbate; V L Taylor
Journal: Brain Res Date: 1990-10-08 Impact factor: 3.252

10. Ecstasy, 3-4 methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia.

Authors: I S Chadwick; P D Curry; A Linsley; A J Freemont; B Doran
Journal: J R Soc Med Date: 1991-06 Impact factor: 18.000

13 in total

Review 1. Street drug abuse leading to critical illness.

Authors: Babak Mokhlesi; Prasad S Garimella; Aaron Joffe; Valerie Velho
Journal: Intensive Care Med Date: 2004-03-04 Impact factor: 17.440

2. Death following recreational use of designer drug "bath salts" containing 3,4-Methylenedioxypyrovalerone (MDPV).

Authors: Brittany L Murray; Christine M Murphy; Michael C Beuhler
Journal: J Med Toxicol Date: 2012-03

Review 3. The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs.

Authors: H Kalant
Journal: CMAJ Date: 2001-10-02 Impact factor: 8.262

4. Role of the serotonin 5-HT2A receptor in the hyperlocomotive and hyperthermic effects of (+)-3,4-methylenedioxymethamphetamine.

Authors: David V Herin; Shijing Liu; Thomas Ullrich; Kenner C Rice; Kathryn A Cunningham
Journal: Psychopharmacology (Berl) Date: 2004-10-23 Impact factor: 4.530

5. "Ecstasy" associated deaths: what is a fatal concentration ? Analysis of a case series.

Authors: C M Milroy
Journal: Forensic Sci Med Pathol Date: 2011-01-25 Impact factor: 2.007

6. Thermoregulatory effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans.

Authors: Robert R Freedman; Chris-Ellyn Johanson; Manuel E Tancer
Journal: Psychopharmacology (Berl) Date: 2005-11-09 Impact factor: 4.530

Review 7. The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3,4-methylenedioxymethamphetamine.

Authors: Edward M Mills; Daniel E Rusyniak; Jon E Sprague
Journal: J Mol Med (Berl) Date: 2004-11-10 Impact factor: 4.599

8. Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone).

Authors: M L Miller; K M Creehan; D Angrish; D J Barlow; K L Houseknecht; T J Dickerson; M A Taffe
Journal: Drug Alcohol Depend Date: 2012-07-23 Impact factor: 4.492

9. Attenuation of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-induced rhabdomyolysis with alpha1- plus beta3-adrenoreceptor antagonists.

Authors: Jon E Sprague; Robert E Brutcher; Edward M Mills; David Caden; Daniel E Rusyniak
Journal: Br J Pharmacol Date: 2004-05-24 Impact factor: 8.739

10. Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat.

Authors: J E Malberg; L S Seiden
Journal: J Neurosci Date: 1998-07-01 Impact factor: 6.167