Literature DB >> 22271565

Death following recreational use of designer drug "bath salts" containing 3,4-Methylenedioxypyrovalerone (MDPV).

Brittany L Murray1, Christine M Murphy, Michael C Beuhler.   

Abstract

INTRODUCTION: 3,4-Methylenedioxypyrovalerone (MDPV) is a designer stimulant drug that has gained popularity in the USA. Although adverse effects of MDPV have been described, to our knowledge, this is the first reported death. CASE REPORT: We report the case of a 40-year-old male who injected and snorted "bath salts" containing MDPV and subsequently became agitated, aggressive, and experienced a cardiac arrest. He was resuscitated after his initial arrest; however, he developed hyperthermia, rhabdomyolysis, coagulopathy, acidosis, anoxic brain injury, and subsequently died. DISCUSSION: This is the first case in the medical literature to report death due to isolated confirmed MDPV intoxication. The manner of death is also consistent with excited delirium syndrome.

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Year:  2012        PMID: 22271565      PMCID: PMC3550226          DOI: 10.1007/s13181-011-0196-9

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  22 in total

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2.  Bath salts as a "legal high".

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6.  Absorption and urinary execretion of trimethoprim, sulfamethoxazole, and trimethoprim-sulfamethoxazole: results with single doses in normal young adults and preliminary observations during therapy with trimethoprim-sulfamethoxazole.

Authors:  M C Bach; O Gold; M Finland
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7.  Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MDPV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry.

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8.  Emergency department visits after use of a drug sold as "bath salts"--Michigan, November 13, 2010-March 31, 2011.

Authors: 
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9.  [Analysis of designer drugs detected in the products purchased in fiscal year 2006].

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Authors:  Peter C Meltzer; David Butler; Jeffrey R Deschamps; Bertha K Madras
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  61 in total

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Journal:  Drug Alcohol Depend       Date:  2012-06-03       Impact factor: 4.492

2.  Emerging drugs of abuse: what was new yesterday is new today.

Authors:  Mark B Mycyk
Journal:  J Med Toxicol       Date:  2012-03

3.  Intoxications associated with agitation, tachycardia, hypertension, and Fever: differential diagnosis, evaluation, and management.

Authors:  Christopher J Keary; Shamim H Nejad; J J Rasimas; Theodore A Stern
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5.  The availability and depiction of synthetic cathinones (bath salts) on the Internet: Do online suppliers employ features to maximize purchases?

Authors:  Kathleen Meyers; Övgü Kaynak; Elena Bresani; Brenda Curtis; Ashley McNamara; Kristine Brownfield; Kimberly C Kirby
Journal:  Int J Drug Policy       Date:  2015-01-16

Review 6.  Synthetic cathinones ("bath salts").

Authors:  Matthew L Banks; Travis J Worst; Daniel E Rusyniak; Jon E Sprague
Journal:  J Emerg Med       Date:  2014-02-22       Impact factor: 1.484

7.  Effects of orally self-administered bath salt constituent 3,4-methylenedioxypyrovalerone (MDPV) in mice.

Authors:  Brenda M Gannon; Lauren N Russell; Meet S Modi; Kenner C Rice; William E Fantegrossi
Journal:  Drug Alcohol Depend       Date:  2017-08-04       Impact factor: 4.492

8.  Postmortem detection of 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine] in fluids and tissues determined by high performance liquid chromatography with tandem mass spectrometry from a traumatic death.

Authors:  Justin L Poklis; Kelly G Devers; Elise F Arbefeville; Julia M Pearson; Eric Houston; Alphonse Poklis
Journal:  Forensic Sci Int       Date:  2013-10-18       Impact factor: 2.395

9.  Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and methylenedioxymethamphetamine.

Authors:  Dawn E Muskiewicz; Federico Resendiz-Gutierrez; Omar Issa; F Scott Hall
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10.  In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV).

Authors:  Ana Margarida Araújo; Márcia Carvalho; Vera Marisa Costa; José Alberto Duarte; Ricardo Jorge Dinis-Oliveira; Maria de Lourdes Bastos; Paula Guedes de Pinho; Félix Carvalho
Journal:  Arch Toxicol       Date:  2020-11-19       Impact factor: 5.153

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