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Literature DB >> 885534

Localization of HLA on the short arm of chromosome 6.

M H Breuning, E M van den Berg-Loonen, L F Bernini, J B Bijlsma, E van Loghem, P Meera Khan, L E Nijenhuis.

Abstract

A detailed marker gene study in a large Dutch kindred segregating for a reciprocal translocation between the chromosomes 6 and 20, t(6;20) (p21; p13), revealed a close linkage between the HLA genes and the breakpoint on the short arm of 6. During this study an apparent peak lod score of 2.9 was obtained at a recombination value of 0.05 for a linkage between HLA and the breakpoint, indicating that the chromosomal region, carrying the HLA genes, is situated near the breakpoint in band 6p21 close to the transition to 6p22.

Entities: Gene

Mesh：

Substances：

Year: 1977 PMID： 885534 DOI： 10.1007/bf00393575

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

22 in total

1. Chromosome preparations of leukocytes cultured from human peripheral blood.

Authors: P S MOORHEAD; P C NOWELL; W J MELLMAN; D M BATTIPS; D A HUNGERFORD
Journal: Exp Cell Res Date: 1960-09 Impact factor: 3.905

2. The distribution of esterase D variants in different ethnic groups.

Authors: A C Ebeli-Struijk; E M Wurzer-Figurelli; F Ajmar; P Meera Khan
Journal: Hum Genet Date: 1976-12-15 Impact factor: 4.132

3. Cytological assessment of meiotic exchange in a human male with a pericentric inversion of chromosome No. 4.

Authors: A G Van der Linden; P L Pearson; J J Van de Kamp
Journal: Cytogenet Cell Genet Date: 1975

4. Assignment of the major histocompatibility complex to chromosome No. 6 in a family with a pericentric inversion.

Authors: L U Lamm; U Friedrich; C B Petersen; J Jorgensen; J Nielsen; A J Therkelsen; F Kissmeyer-Nielsen
Journal: Hum Hered Date: 1974 Impact factor: 0.444

5. A simple method for R banding of human chromosomes, showing a pH-dependent connection between R and G bands.

Authors: J Sehested
Journal: Humangenetik Date: 1974-01-22

6. Chiasma distribution at diakinesis in the normal human male.

Authors: M Hultén
Journal: Hereditas Date: 1974 Impact factor: 3.271

7. On the orientation of the HL-A region and the PGM3 locus in the chromosome.

Authors: L U Lamm; F Kissmeyer-Nielsen; A Svejgaard; G B Petersen; E Thorsby; W Mayr; C Högman
Journal: Tissue Antigens Date: 1972

8. Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man.

Authors: T R Chen; F A McMorris; R Creagan; F Ricciuti; J Tischfield; F Ruddle
Journal: Am J Hum Genet Date: 1973-03 Impact factor: 11.025

9. Rapid detection of 6-phosphogluconate dehydrogenase variants by electrophoresis on cellulose acetate gel.

Authors: P Meera Khan; M C Rattazzi
Journal: Biochem Genet Date: 1968-11 Impact factor: 1.890

10. Chromosome assignments of genes in man using mouse-human somatic cell hybrids: mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to chromosome 6.

Authors: R Creagan; J Tischfield; F Ricciuti; F H Ruddle
Journal: Humangenetik Date: 1973-12-10

12 in total

1. Partial trisomy 6p.

Authors: A Bernheim; R Berger; G Vaugier; J C Thieffry; Y Matet
Journal: Hum Genet Date: 1979-04-17 Impact factor: 4.132

2. Linkage studies on the human Pi, Gm, GLO, and HLA genes.

Authors: K Bender; C R Müller; A Schmidt; U Strohmaier; T F Wienker
Journal: Hum Genet Date: 1979-06-19 Impact factor: 4.132

3. Some medical applications of the oxford scanning proton microprobe.

Authors: D J Vaux; G W Grime; F Watt
Journal: Biol Trace Elem Res Date: 1987-08 Impact factor: 3.738

4. Molecular analysis distinguishes two HLA-DR3-bearing major histocompatibility complex extended haplotypes.

Authors: M Z Wescott; Z L Awdeh; E J Yunis; C A Alper
Journal: Immunogenetics Date: 1987 Impact factor: 2.846

5. Regional localization for HLA by recombination with a fragile site at 6p23.

Authors: J C Mulley; J Hay; L J Sheffield; G R Sutherland
Journal: Am J Hum Genet Date: 1983-11 Impact factor: 11.025

6. Analysis of the HLA-ABC linkage disequilibrium: decreasing strength of gametic association with increasing map distance.

Authors: C Hiller; M Bischoff; A Schmidt; K Bender
Journal: Hum Genet Date: 1978-04-24 Impact factor: 4.132

7. Linkage investigations in two families with hereditary ataxia.

Authors: J Van Rossum; H Veenema; L N Went
Journal: J Neurol Neurosurg Psychiatry Date: 1981-06 Impact factor: 10.154

8. Orientation of loci within the human major histocompatibility complex by chromosomal in situ hybridization.

Authors: C C Morton; I R Kirsch; W E Nance; G A Evans; A J Korman; J L Strominger
Journal: Proc Natl Acad Sci U S A Date: 1984-05 Impact factor: 11.205

9. Linkage disequilibrium of HLA-SB1 with the HLA-A1, B8, DR3, SCO1 and of HLA-SB4 with the HLA-A26, Bw38, Dw10, DR4, SC21 extended haplotypes.

Authors: Y Matsui; S M Alosco; Z Awdeh; R J Duquesnoy; P L Page; R J Hartzman; C A Alper; E J Yunis
Journal: Immunogenetics Date: 1984 Impact factor: 2.846

10. Urinary pepsinogen isozymes: a highly polymorphic locus in man.

Authors: R T Taggart; R C Karn; A D Merritt; P L Yu; P M Conneally
Journal: Hum Genet Date: 1979-11 Impact factor: 4.132