Literature DB >> 8851622

Bleomycin therapy of experimental disseminated candidiasis in mice.

J R Graybill1, R Bocanegra, A Fothergill, M G Rinaldi.   

Abstract

Bleomycin, an antineoplastic agent, was found to be very effective in vitro against a variety of fungi, including Candida albicans. Mice were infected with C. albicans intravenously and then treated with various doses of bleomycin. No efficacy was shown by either prolongation of survival or reduction of tissue counts.

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Year:  1996        PMID： 8851622      PMCID： PMC163209     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model.

Authors:  C W Moore
Journal:  J Bacteriol       Date:  1991-06       Impact factor: 3.490

2.  Immunoregulatory cytokine production by tumor-bearing rat spleen cells and its modulation by bleomycin.

Authors:  M Micallef
Journal:  Anticancer Drugs       Date:  1993-04       Impact factor: 2.248

3.  Bleomycin affects cell wall anchorage of mannoproteins in Saccharomyces cerevisiae.

Authors:  R Beaudouin; S T Lim; J A Steide; M Powell; J McKoy; A J Pramanik; E Johnson; C W Moore; P N Lipke
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

4.  Correlation of in vitro azole susceptibility with in vivo response in a murine model of cryptococcal meningitis.

Authors:  J D Velez; R Allendoerfer; M Luther; M G Rinaldi; J R Graybill
Journal:  J Infect Dis       Date:  1993-08       Impact factor: 5.226

5.  Lesions and preferential initial localization of [S-methyl-3H]bleomycin A2 on Saccharomyces cerevisiae cell walls and membranes.

Authors:  C W Moore; R Del Valle; J McKoy; A Pramanik; R E Gordon
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

6.  Cleavage of tRNA by Fe(II)-bleomycin.

Authors:  A Hüttenhofer; S Hudson; H F Noller; P K Mascharak
Journal:  J Biol Chem       Date:  1992-12-05       Impact factor: 5.157

7.  Changes in distribution, morphology, and tumor necrosis factor-alpha secretion of alveolar macrophage subpopulations during the development of bleomycin-induced pulmonary fibrosis.

Authors:  M P Everson; D B Chandler
Journal:  Am J Pathol       Date:  1992-02       Impact factor: 4.307

8.  Lung cytokine production in bleomycin-induced pulmonary fibrosis.

Authors:  S H Phan; S L Kunkel
Journal:  Exp Lung Res       Date:  1992 Jan-Mar       Impact factor: 2.459

9.  Bleomycin-induced DNA repair by Saccharomyces cerevisiae ATP-dependent polydeoxyribonucleotide ligase.

Authors:  C W Moore
Journal:  J Bacteriol       Date:  1988-10       Impact factor: 3.490

10.  Potentiation of bleomycin cytotoxicity in Saccharomyces cerevisiae.

Authors:  C W Moore
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191
  10 in total
  6 in total

Review 1.  Antifungal activity of nonantifungal drugs.

Authors:  J Afeltra; P E Verweij
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2003-06-26       Impact factor: 3.267

2.  Group I intron renders differential susceptibility of Candida albicans to Bleomycin.

Authors:  Prathiba Jayaguru; Malathi Raghunathan
Journal:  Mol Biol Rep       Date:  2006-11-07       Impact factor: 2.316

Review 3.  Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species.

Authors:  Sharon C-A Chen; Russell E Lewis; Dimitrios P Kontoyiannis
Journal:  Virulence       Date:  2011-07-01       Impact factor: 5.882

4.  Role of the homologous recombination genes RAD51 and RAD59 in the resistance of Candida albicans to UV light, radiomimetic and anti-tumor compounds and oxidizing agents.

Authors:  Fátima García-Prieto; Jonathan Gómez-Raja; Encarnación Andaluz; Richard Calderone; Germán Larriba
Journal:  Fungal Genet Biol       Date:  2010-03-03       Impact factor: 3.495

Review 5.  Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.

Authors:  M E Cardenas; M C Cruz; M Del Poeta; N Chung; J R Perfect; J Heitman
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

6.  A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus.

Authors:  Sarah R Beattie; Damian J Krysan
Journal:  mSphere       Date:  2021-08-18       Impact factor: 4.389
  6 in total

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