Literature DB >> 2459112

Bleomycin-induced DNA repair by Saccharomyces cerevisiae ATP-dependent polydeoxyribonucleotide ligase.

C W Moore1.   

Abstract

In contrast to ligase-deficient (cdc9) Saccharomyces cerevisiae, which did not rejoin bleomycin-induced DNA breaks, ligase-proficient (CDC9) yeast cells eliminated approximately 90% of DNA breaks within 90 to 120 min after treatment. Experimental conditions restricted enzymatic removal of the unusual 3'-phosphoglycolate termini in DNA cleaved by bleomycin and involved doses producing equivalent numbers of DNA breaks or doses producing equivalent killing.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2459112      PMCID： PMC211556          DOI： 10.1128/jb.170.10.4991-4994.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  38 in total

1.  Review and evaluation of molecular weight calculations from the sedimentation profiles of irradiated DNA.

Authors:  U K Ehmann; J T Lett
Journal:  Radiat Res       Date:  1973-04       Impact factor: 2.841

2.  Interactions of bleomycin with DNA.

Authors:  A P Grollman; M Takeshita
Journal:  Adv Enzyme Regul       Date:  1980

3.  Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

Authors:  L Giloni; M Takeshita; F Johnson; C Iden; A P Grollman
Journal:  J Biol Chem       Date:  1981-08-25       Impact factor: 5.157

4.  Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants.

Authors:  L H Hartwell; R K Mortimer; J Culotti; M Culotti
Journal:  Genetics       Date:  1973-06       Impact factor: 4.562

5.  Rapid and slow DNA rejoining in nondividing human diploid fibroblasts treated with bleomycin and ionizing radiation.

Authors:  C W Moore; J B Little
Journal:  Cancer Res       Date:  1985-05       Impact factor: 12.701

6.  Ligase-deficient yeast cells exhibit defective DNA rejoining and enhanced gamma ray sensitivity.

Authors:  C W Moore
Journal:  J Bacteriol       Date:  1982-06       Impact factor: 3.490

7.  The DNA repair capability of cdc9, the Saccharomyces cerevisiae mutant defective in DNA ligase.

Authors:  L H Johnston
Journal:  Mol Gen Genet       Date:  1979-02-16

8.  Modulation of bleomycin cytotoxicity.

Authors:  C W Moore
Journal:  Antimicrob Agents Chemother       Date:  1982-04       Impact factor: 5.191

9.  Enhanced mitotic recombination in a ligase-defective mutant of the yeast Saccharomyces cerevisiae.

Authors:  J C Game; L H Johnston; R C von Borstel
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

10.  Macromolecule synthesis in temperature-sensitive mutants of yeast.

Authors:  L H Hartwell
Journal:  J Bacteriol       Date:  1967-05       Impact factor: 3.490
View more
  6 in total

1.  Growth phase dependency of chromatin cleavage and degradation by bleomycin.

Authors:  C W Moore; C S Jones; L A Wall
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

2.  Bleomycin affects cell wall anchorage of mannoproteins in Saccharomyces cerevisiae.

Authors:  R Beaudouin; S T Lim; J A Steide; M Powell; J McKoy; A J Pramanik; E Johnson; C W Moore; P N Lipke
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

3.  Bleomycin therapy of experimental disseminated candidiasis in mice.

Authors:  J R Graybill; R Bocanegra; A Fothergill; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

4.  Lesions and preferential initial localization of [S-methyl-3H]bleomycin A2 on Saccharomyces cerevisiae cell walls and membranes.

Authors:  C W Moore; R Del Valle; J McKoy; A Pramanik; R E Gordon
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

5.  Effects of bleomycin on growth kinetics and survival of Saccharomyces cerevisiae: a model of repair pathways.

Authors:  D J Keszenman; V A Salvo; E Nunes
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

6.  Potentiation of bleomycin cytotoxicity in Saccharomyces cerevisiae.

Authors:  C W Moore
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.