Literature DB >> 1710619

Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model.

C W Moore1.   

Abstract

Direct selection for 12 mutations (blm) conferring hypersensitivities to lethal effects of bleomycins in Saccharomyces cerevisiae resulted in mutants exhibiting cross-hypersensitivity to ionizing radiation and hydrogen peroxide. Remaining mutations did not confer cross-hypersensitivity to radiation. All blm mutations were recessive, except codominant blm3-1, and were assigned to seven complementation groups.

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Year:  1991        PMID： 1710619      PMCID： PMC207981          DOI： 10.1128/jb.173.11.3605-3608.1991

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  25 in total

1.  Role of DNA sequences in genetic recombination in the iso-1-cytochrome c gene of yeast. I. Discrepancies between physical distances and genetic distances determined by five mapping procedures.

Authors:  C W Moore; F Sherman
Journal:  Genetics       Date:  1975-03       Impact factor: 4.562

2.  Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli.

Authors:  B Demple; A Johnson; D Fung
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

3.  Enhanced bleomycin-mediated damage of DNA opposite charged nicks. A model for bleomycin-directed double strand scission of DNA.

Authors:  T J Keller; N J Oppenheimer
Journal:  J Biol Chem       Date:  1987-11-05       Impact factor: 5.157

4.  Interactions of bleomycin with DNA.

Authors:  A P Grollman; M Takeshita
Journal:  Adv Enzyme Regul       Date:  1980

5.  Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

Authors:  L Giloni; M Takeshita; F Johnson; C Iden; A P Grollman
Journal:  J Biol Chem       Date:  1981-08-25       Impact factor: 5.157

6.  Yeast DNA 3'-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics.

Authors:  A W Johnson; B Demple
Journal:  J Biol Chem       Date:  1988-12-05       Impact factor: 5.157

7.  Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage.

Authors:  A W Johnson; B Demple
Journal:  J Biol Chem       Date:  1988-12-05       Impact factor: 5.157

8.  Aphidicolin-sensitive DNA repair synthesis in human fibroblasts damaged with bleomycin is distinct from UV-induced repair.

Authors:  J A DiGiuseppe; D J Hunting; S L Dresler
Journal:  Carcinogenesis       Date:  1990-06       Impact factor: 4.944

9.  Analysis of products formed during bleomycin-mediated DNA degradation.

Authors:  N Murugesan; C Xu; G M Ehrenfeld; H Sugiyama; R E Kilkuskie; L O Rodriguez; L H Chang; S M Hecht
Journal:  Biochemistry       Date:  1985-10-08       Impact factor: 3.162

10.  Bleomycin-induced DNA repair synthesis in permeable human fibroblasts: mediation of long-patch and short-patch repair by distinct DNA polymerases.

Authors:  J A DiGiuseppe; S L Dresler
Journal:  Biochemistry       Date:  1989-11-28       Impact factor: 3.162
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  11 in total

1.  PA200, a nuclear proteasome activator involved in DNA repair.

Authors:  Vicença Ustrell; Laura Hoffman; Gregory Pratt; Martin Rechsteiner
Journal:  EMBO J       Date:  2002-07-01       Impact factor: 11.598

2.  Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.

Authors:  Jack Iwanczyk; Kianoush Sadre-Bazzaz; Katherine Ferrell; Elena Kondrashkina; Timothy Formosa; Christopher P Hill; Joaquin Ortega
Journal:  J Mol Biol       Date:  2006-08-09       Impact factor: 5.469

3.  DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae.

Authors:  C W Moore; J McKoy; M Dardalhon; D Davermann; M Martinez; D Averbeck
Journal:  Genetics       Date:  2000-03       Impact factor: 4.562

4.  Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin.

Authors:  A Leduc; C H He; D Ramotar
Journal:  Mol Genet Genomics       Date:  2003-02-12       Impact factor: 3.291

5.  Bleomycin affects cell wall anchorage of mannoproteins in Saccharomyces cerevisiae.

Authors:  R Beaudouin; S T Lim; J A Steide; M Powell; J McKoy; A J Pramanik; E Johnson; C W Moore; P N Lipke
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

6.  Bleomycin therapy of experimental disseminated candidiasis in mice.

Authors:  J R Graybill; R Bocanegra; A Fothergill; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

7.  The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants.

Authors:  J Y Masson; D Ramotar
Journal:  Mol Cell Biol       Date:  1996-05       Impact factor: 4.272

8.  Effects of bleomycin on growth kinetics and survival of Saccharomyces cerevisiae: a model of repair pathways.

Authors:  D J Keszenman; V A Salvo; E Nunes
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

Review 9.  Protective mechanisms against the antitumor agent bleomycin: lessons from Saccharomyces cerevisiae.

Authors:  Dindial Ramotar; Huijie Wang
Journal:  Curr Genet       Date:  2003-04-16       Impact factor: 3.886

10.  Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of action.

Authors:  Kevin M Doherty; Leah D Pride; James Lukose; Brian E Snydsman; Ronald Charles; Ajay Pramanik; Eric G Muller; David Botstein; Carol Wood Moore
Journal:  G3 (Bethesda)       Date:  2012-08-01       Impact factor: 3.154
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