| Literature DB >> 8848835 |
S Hayashi1, Y Murakami, S Matsufuji.
Abstract
Antizyme plays an important regulatory role in the synthesis of ornithine decarboxylase (ODC), a key enzyme of polyamine synthesis in higher animals. As well as inactivating polyamine uptake, antizyme is induced by polyamine-enhanced translational frameshifting, and binds to ODC, accelerating its ATP-dependent degradation, a process catalysed by the 26S proteasome.Entities:
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Year: 1996 PMID: 8848835
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807