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Literature DB >> 883955

Retained folates in the rat.

Abstract

The retention of radioactivity after doses of 14C- and 3H-labelled folic acid is described. Radioactivity was retained in liver, kidney and gut of rats for some time after administration of the dose. The retained radioactivity could not be displaced by large doses of unlabelled folic acid or unlabelled 5-methyltetrahydrofolate. 14C- and 3H-labbelled folates showed similar chromatographic behaviour onion-exchange chromatography to 5-methyltetrahydrofolate, and on ion-exchange and gel-permeation chromatography to synthetic pteroylhepta-gamma-glutamate.

Entities: Chemical Species

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Year: 1977 PMID： 883955 PMCID： PMC1164837 DOI： 10.1042/bj1640601

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

19 in total

1. High-molecular-weight folates of rat liver.

Authors: P A Barford; J A Blair; F J Staff
Journal: Biochem Soc Trans Date: 1976 Impact factor: 5.407

2. Rat brain folate identification.

Authors: T Brody; Y S Shin; E L Stokstad
Journal: J Neurochem Date: 1976-08 Impact factor: 5.372

3. The pH-dependent rearrangements of formyltetrahydrofolates and their nutritional implications.

Authors: J R Beavon; J A Blair
Journal: Br J Nutr Date: 1972-11 Impact factor: 3.718

4. Effect of methionine on specific folate coenzyme pools in vitamin B 12 deficient and supplemented rats.

Authors: S W Thenen; E L Stokstad
Journal: J Nutr Date: 1973-03 Impact factor: 4.798

5. Hydroxylated derivatives of 5-methyl-5,6,7,8-tetrahydrofolate.

Authors: G R Gapski; J M Whiteley; F M Huennekens
Journal: Biochemistry Date: 1971-07-20 Impact factor: 3.162

6. Naturally occurring folates in the blood and liver of the rat.

Authors: O D Bird; V M McGlohon; J W Vaitkus
Journal: Anal Biochem Date: 1965-07 Impact factor: 3.365

Review 7. Synthesis and breakdown of natural folates (folate polyglutamates).

Authors: A V Hoffbrand
Journal: Prog Hematol Date: 1975

8. A convenient method for the preparation of dl-5-methyltetrahydrofolic acid (dl-5-methyl-5,6,7,8-tetrahydropteroyl-L-monoglutamic acid).

Authors: J A Blair; K J Saunders
Journal: Anal Biochem Date: 1970-04 Impact factor: 3.365

9. The identification of the forms of folate found in the liver, kidney and intestine of the monkey and their biosynthesis from exogenous pteroylglutamate (folic acid).

Authors: J P Brown; G E Davidson; J M Scott
Journal: Biochim Biophys Acta Date: 1974-03-20

10. The reaction of tetrahydropteroylglutamic acid and related hydropteridines with formaldehyde.

Authors: R L BLAKLEY
Journal: Biochem J Date: 1959-08 Impact factor: 3.857

8 in total

1. The metabolism of 5-methyltetrahydropteroyl-L-glutamic acid and its oxidation products in the rat.

Authors: J C Kennelly; J A Blair; A E Pheasant
Journal: Biochem J Date: 1982-08-15 Impact factor: 3.857

2. The metabolic fate of (2-14C)folic acid and a mixture of (2-14C)- and (3',5',9-3h)-folic acid in the rat.

Authors: P A Barford; F J Staff; J A Blair
Journal: Biochem J Date: 1978-08-15 Impact factor: 3.857

3. The identification of the folate conjugates found in rat liver 48 h after the administration of radioactively labelled folate tracers.

Authors: M J Connor; J A Blair
Journal: Biochem J Date: 1980-01-15 Impact factor: 3.857