Literature DB >> 8809481

Performance evaluation of the FACSCount System: a dedicated system for clinical cellular analysis.

K Strauss1, I Hannet, S Engels, A Shiba, D M Ward, S Ullery, M G Jinguji, J Valinsky, D Barnett, A Orfao, L Kestens.   

Abstract

Flow cytometers are instruments that can determine multiparameter data simultaneously and have a great potential in providing unique information about cells. The FACSCount System is designed as the first dedicated flow cytometer for the clinical laboratory. Its current configuration provides CD4, CD8, and CD3 absolute counts from 100 microliters of whole blood. Adapting the FACSCount System to the clinical setting are minimal sample handling, lysis free cell preparation, automated fluorescence gating, built-in calibrated reference beads, and appropriate error code reporting. Quality control checks ensure that reported CD4 counts, important for clinical follow-up and patient management, are accurate, precise, and reproducible across instruments over time.

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Year:  1996        PMID: 8809481     DOI: 10.1002/(SICI)1097-0320(19960315)26:1<52::AID-CYTO8>3.0.CO;2-I

Source DB:  PubMed          Journal:  Cytometry        ISSN: 0196-4763


  22 in total

1.  Use of formalin-fixed, propidium iodide-stained human leukocytes as a standard for enumerating CD4+ T lymphocytes in a single-platform assay.

Authors:  G M Harrison; A J Bennett; M Moody; G F Read; P E Williams
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

2.  Evaluation of a new single-parameter volumetric flow cytometer (CyFlow(green)) for enumeration of absolute CD4+ T lymphocytes in human immunodeficiency virus type 1-infected Thai patients.

Authors:  Kovit Pattanapanyasat; Surada Lerdwana; Egarit Noulsri; Thanyanan Chaowanachan; Punneeporn Wasinrapee; Natthaga Sakulploy; Vallerut Pobkeeree; Orapin Suksripanich; Sombat Thanprasertsuk; Thomas J Spira; Jordan W Tappero; William C Levine
Journal:  Clin Diagn Lab Immunol       Date:  2005-12

3.  Clinical field site evaluation of the FACSCount for absolute CD3+, CD3+ CD4+, and CD3+ CD8+ cell count determinations in Thailand.

Authors:  N L Young; P Ponglertnapakorn; N Shaffer; K Srisak; T Chaowanachan; V On-Thern; C Kittinunvorakoon; A Bunwattanakul; S Suksaweang; V Pobkeeree; J Punnotok; T D Mastro
Journal:  Clin Diagn Lab Immunol       Date:  1997-11

4.  Single Versus Dual Platform Analysis for Hematopoietic Stem Cell Enumeration Using ISHAGE Protocol.

Authors:  Rahul Naithani; Nitin Dayal; Gaurav Dixit
Journal:  Indian J Hematol Blood Transfus       Date:  2016-12-01       Impact factor: 0.900

5.  A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects.

Authors:  Xuanhong Cheng; Daniel Irimia; Meredith Dixon; Kazuhiko Sekine; Utkan Demirci; Lee Zamir; Ronald G Tompkins; William Rodriguez; Mehmet Toner
Journal:  Lab Chip       Date:  2006-11-24       Impact factor: 6.799

Review 6.  Diagnosis of Human Immunodeficiency Virus Infection.

Authors:  Bharat S Parekh; Chin-Yih Ou; Peter N Fonjungo; Mireille B Kalou; Erin Rottinghaus; Adrian Puren; Heather Alexander; Mackenzie Hurlston Cox; John N Nkengasong
Journal:  Clin Microbiol Rev       Date:  2018-11-28       Impact factor: 26.132

7.  Low CD4+ T-lymphocyte values in human immunodeficiency virus-negative adults in Botswana.

Authors:  Hermann Bussmann; C William Wester; Kereng V Masupu; Trevor Peter; Sarah M Gaolekwe; Soyeon Kim; Ann Marie Reich; Sam Ahn; Ying Wu; Ibou Thior; Max Essex; Richard Marlink
Journal:  Clin Diagn Lab Immunol       Date:  2004-09

8.  Evaluation of Dynabeads and Cytospheres compared with flow cytometry to enumerate CD4+ T cells in HIV-infected Ugandans on antiretroviral therapy.

Authors:  Fred Lutwama; Ronnie Serwadda; Harriet Mayanja-Kizza; Hasan M Shihab; Allan Ronald; Moses R Kamya; David Thomas; Elizabeth Johnson; Thomas C Quinn; Richard D Moore; Lisa A Spacek
Journal:  J Acquir Immune Defic Syndr       Date:  2008-07-01       Impact factor: 3.731

Review 9.  CD4 immunophenotyping in HIV infection.

Authors:  David Barnett; Brooke Walker; Alan Landay; Thomas N Denny
Journal:  Nat Rev Microbiol       Date:  2008-11       Impact factor: 60.633

Review 10.  Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings.

Authors:  Catherine E Majors; Chelsey A Smith; Mary E Natoli; Kathryn A Kundrod; Rebecca Richards-Kortum
Journal:  Lab Chip       Date:  2017-10-11       Impact factor: 6.799

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