Literature DB >> 8792625

Tolypodiol, an antiinflammatory diterpenoid from the cyanobacterium Tolypothrix nodosa.

M R Prinsep1, R A Thomson, M L West, B L Wylie.   

Abstract

A new diterpenoid, tolypodiol (1), has been isolated from the terrestrial cyanobacterium Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The monoacetate derivative 2 was prepared. Tolypodiol (1) and its monoacetate derivative 2 show potent antiinflammatory activity in the mouse ear edema assay.

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Year:  1996        PMID： 8792625     DOI： 10.1021/np9602574

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

Review 1.  Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.

Authors:  George E Chlipala; Shunyan Mo; Jimmy Orjala
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus.

Authors:  Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Kenneth I Hardcastle; Craig R Fairchild; William Aalbersberg; Carmen Raventos-Suarez; Mark E Hay
Journal:  Org Lett       Date:  2005-11-10       Impact factor: 6.005

3.  6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2.

Authors:  Joshua R Gurr; Timothy J O'Donnell; Yuheng Luo; Wesley Y Yoshida; Mary L Hall; Alejandro M S Mayer; Rui Sun; Philip G Williams
Journal:  J Nat Prod       Date:  2020-04-13       Impact factor: 4.050

4.  Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

Authors:  Amy L Lane; Elizabeth P Stout; Mark E Hay; Anne C Prusak; Kenneth Hardcastle; Craig R Fairchild; Scott G Franzblau; Karine Le Roch; Jacques Prudhomme; William Aalbersberg; Julia Kubanek
Journal:  J Org Chem       Date:  2007-08-23       Impact factor: 4.354

5.  Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate.

Authors:  Francisco A Villa; Kelly Lieske; Lena Gerwick
Journal:  Eur J Pharmacol       Date:  2009-12-16       Impact factor: 4.432

6.  A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.

Authors:  Annalisa Macagno; Monica Molteni; Andrea Rinaldi; Francesco Bertoni; Antonio Lanzavecchia; Carlo Rossetti; Federica Sallusto
Journal:  J Exp Med       Date:  2006-05-22       Impact factor: 14.307

Review 7.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

8.  Draft Genome Sequence of Bioactive-Compound-Producing Cyanobacterium Tolypothrix campylonemoides Strain VB511288.

Authors:  Subhadeep Das; Deeksha Singh; Madhavi Madduluri; Mathu Malar Chandrababunaidu; Akash Gupta; Siba Prasad Adhikary; Sucheta Tripathy
Journal:  Genome Announc       Date:  2015-04-02

Review 9.  Terpenoids and their biosynthesis in cyanobacteria.

Authors:  Bagmi Pattanaik; Pia Lindberg
Journal:  Life (Basel)       Date:  2015-01-21

10.  The conifer biomarkers dehydroabietic and abietic acids are widespread in Cyanobacteria.

Authors:  Maria Sofia Costa; Adriana Rego; Vitor Ramos; Tiago B Afonso; Sara Freitas; Marco Preto; Viviana Lopes; Vitor Vasconcelos; Catarina Magalhães; Pedro N Leão
Journal:  Sci Rep       Date:  2016-03-21       Impact factor: 4.379
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