Literature DB >> 8787855

Implantable pumps for drug delivery to the brain.

S Bakhshi1, R B North.   

Abstract

This article reviews the role of implantable pumps in the treatment of CNS tumors. Systemic administration of chemotherapeutic agents has been associated with various problems, including adverse systemic effects and decreased concentration of the drug at the target site. Continuous infusion of chemotherapeutic agents with implantable pumps have been used in an attempt to overcome these problems. Various different chemotherapeutic agents have been used for this purpose, and catheters have been placed in the intraspinal, intraventricular and intratumoral locations.

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Year:  1995        PMID: 8787855     DOI: 10.1007/bf01060219

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  56 in total

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Journal:  Neurosurgery       Date:  1984-12       Impact factor: 4.654

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  8 in total

Review 1.  Advances in image-guided intratumoral drug delivery techniques.

Authors:  Luis Solorio; Ravi B Patel; Hanping Wu; Tianyi Krupka; Agata A Exner
Journal:  Ther Deliv       Date:  2010-08

Review 2.  Pharmacokinetics following intraventricular administration of chemotherapy in patients with neoplastic meningitis.

Authors:  Gudrun Fleischhack; Ulrich Jaehde; Udo Bode
Journal:  Clin Pharmacokinet       Date:  2005       Impact factor: 6.447

Review 3.  Cytotoxic chemotherapy: advances in delivery, pharmacology, and testing.

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4.  Effects of basic fibroblastic growth factor on the growth of human medulloblastoma xenografts.

Authors:  Pascal Vachon; Christiane Girard; Yves Théorêt
Journal:  J Neurooncol       Date:  2004 Mar-Apr       Impact factor: 4.130

5.  Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primates.

Authors:  Daniela Bumbaca Yadav; Janice A Maloney; Kristin R Wildsmith; Reina N Fuji; William J Meilandt; Hilda Solanoy; Yanmei Lu; Kun Peng; Blair Wilson; Pamela Chan; Kapil Gadkar; Andrew Kosky; Marisa Goo; Ann Daugherty; Jessica A Couch; Thomas Keene; Karen Hayes; Lisa Jungbauer Nikolas; Deanna Lane; Robert Switzer; Eric Adams; Ryan J Watts; Kimberly Scearce-Levie; Saileta Prabhu; Lisa Shafer; Deepak R Thakker; Keith Hildebrand; Jasvinder K Atwal
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Review 6.  Image-guided convection-enhanced delivery platform in the treatment of neurological diseases.

Authors:  Massimo S Fiandaca; John R Forsayeth; Peter J Dickinson; Krystof S Bankiewicz
Journal:  Neurotherapeutics       Date:  2008-01       Impact factor: 7.620

Review 7.  Pharmacokinetics of the carmustine implant.

Authors:  Alison B Fleming; W Mark Saltzman
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

Review 8.  Nanotechnology for delivery of drugs to the brain for epilepsy.

Authors:  Margaret F Bennewitz; W Mark Saltzman
Journal:  Neurotherapeutics       Date:  2009-04       Impact factor: 7.620

  8 in total

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