Literature DB >> 876907

How food and fluid affect drug absorption: results of initial studies.

P G Welling.   

Abstract

The rate and extent of absorption of many drugs may be influenced by the presence of food in the gastrointestinal tract and by the volume of fluid ingested with the dose. In most cases, food appears to inhibit or delay drug absorption. Relatively large fluid volume, on the other hand, appears to enhance absorption.

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Year:  1977        PMID: 876907     DOI: 10.1080/00325481.1977.11712246

Source DB:  PubMed          Journal:  Postgrad Med        ISSN: 0032-5481            Impact factor:   3.840


  13 in total

Review 1.  Pharmacokinetics of drugs in overdose.

Authors:  Y J Sue; M Shannon
Journal:  Clin Pharmacokinet       Date:  1992-08       Impact factor: 6.447

2.  Effects of timing of food and fluid volume on cefetamet pivoxil absorption in healthy normal volunteers.

Authors:  Y K Tam; J Kneer; U C Dubach; K Stoeckel
Journal:  Antimicrob Agents Chemother       Date:  1990-08       Impact factor: 5.191

Review 3.  Influence of food on the bioavailability of drugs.

Authors:  A Melander
Journal:  Clin Pharmacokinet       Date:  1978 Sep-Oct       Impact factor: 6.447

Review 4.  Interactions affecting drug absorption.

Authors:  P G Welling
Journal:  Clin Pharmacokinet       Date:  1984 Sep-Oct       Impact factor: 6.447

5.  The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug.

Authors:  S George; K Dauwe; A McBurney; J Ward
Journal:  Br J Clin Pharmacol       Date:  1983-04       Impact factor: 4.335

6.  Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects.

Authors:  E Wåhlin-Boll; A Melander; G Sartor; B Scherstén
Journal:  Eur J Clin Pharmacol       Date:  1980-10       Impact factor: 2.953

7.  Influence of food and age on the single-dose kinetics and effects of tolbutamide and chlorpropamide.

Authors:  G Sartor; A Melander; B Scherstén; E Wåhlin-Boll
Journal:  Eur J Clin Pharmacol       Date:  1980-04       Impact factor: 2.953

8.  Influence of food on bioavailability of amdinocillin pivoxil.

Authors:  L D Bornemann; S Castellano; A H Lin; D Enthoven; I H Patel
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191

Review 9.  Cefetamet pivoxil clinical pharmacokinetics.

Authors:  R A Blouin; K Stoeckel
Journal:  Clin Pharmacokinet       Date:  1993-09       Impact factor: 6.447

10.  Influence of study design in assessing food effects on absorption of erythromycin base and erythromycin stearate.

Authors:  A R DiSanto; D J Chodos
Journal:  Antimicrob Agents Chemother       Date:  1981-08       Impact factor: 5.191

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