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Literature DB >> 8763960

Overexpression of vsr in Escherichia coli is mutagenic.

K M Doiron¹, S Viau, M Koutroumanis, C G Cupples.

Abstract

Overexpression of vsr in Escherichia coli stimulates transition and frameshift mutations. The pattern of mutations suggests that mutagenesis is due to saturation or inactivation of dam-directed mismatch repair.

Entities: Gene Species

Mesh：

Substances：

Year: 1996 PMID： 8763960 PMCID： PMC178189 DOI： 10.1128/jb.178.14.4294-4296.1996

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

20 in total

1. A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene.

Authors: A Sohail; M Lieb; M Dar; A S Bhagwat
Journal: J Bacteriol Date: 1990-08 Impact factor: 3.490

2. A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations.

Authors: C G Cupples; M Cabrera; C Cruz; J H Miller
Journal: Genetics Date: 1990-06 Impact factor: 4.562

3. Molecular basis of base substitution hotspots in Escherichia coli.

Authors: C Coulondre; J H Miller; P J Farabaugh; W Gilbert
Journal: Nature Date: 1978-08-24 Impact factor: 49.962

4. Effects of amino acid substitutions at the active site in Escherichia coli beta-galactosidase.

Authors: C G Cupples; J H Miller
Journal: Genetics Date: 1988-11 Impact factor: 4.562

5. A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions.

Authors: C G Cupples; J H Miller
Journal: Proc Natl Acad Sci U S A Date: 1989-07 Impact factor: 11.205

6. A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.

Authors: M Singer; T A Baker; G Schnitzler; S M Deischel; M Goel; W Dove; K J Jaacks; A D Grossman; J W Erickson; C A Gross
Journal: Microbiol Rev Date: 1989-03

7. Multicopy single-stranded DNA of Escherichia coli enhances mutation and recombination frequencies by titrating MutS protein.

Authors: W K Maas; C Wang; T Lima; A Hach; D Lim
Journal: Mol Microbiol Date: 1996-02 Impact factor: 3.501

8. Spontaneous mutation at a 5-methylcytosine hotspot is prevented by very short patch (VSP) mismatch repair.

Authors: M Lieb
Journal: Genetics Date: 1991-05 Impact factor: 4.562

9. DNA mismatch-repair in Escherichia coli counteracting the hydrolytic deamination of 5-methyl-cytosine residues.

Authors: R Zell; H J Fritz
Journal: EMBO J Date: 1987-06 Impact factor: 11.598

10. The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors.

Authors: R M Schaaper; M Radman
Journal: EMBO J Date: 1989-11 Impact factor: 11.598

15 in total

1. Growth phase-dependent regulation of Vsr endonuclease may contribute to 5-methylcytosine mutational hot spots in Escherichia coli.

Authors: G Macintyre; P Pitsikas; C G Cupples
Journal: J Bacteriol Date: 1999-07 Impact factor: 3.490

Review 2. Mechanisms of stationary phase mutation: a decade of adaptive mutation.

Authors: P L Foster
Journal: Annu Rev Genet Date: 1999 Impact factor: 16.830

3. Interaction of MutS and Vsr: some dominant-negative mutS mutations that disable methyladenine-directed mismatch repair are active in very-short-patch repair.

Authors: M Lieb; S Rehmat; A S Bhagwat
Journal: J Bacteriol Date: 2001-11 Impact factor: 3.490

4. Very-short-patch repair in Escherichia coli requires the dam adenine methylase.

Authors: D C Bell; C G Cupples
Journal: J Bacteriol Date: 2001-06 Impact factor: 3.490

5. A DNA methyltransferase can protect the genome from postdisturbance attack by a restriction-modification gene complex.

Authors: Noriko Takahashi; Yasuhiro Naito; Naofumi Handa; Ichizo Kobayashi
Journal: J Bacteriol Date: 2002-11 Impact factor: 3.490

9. Levels of the Vsr endonuclease do not regulate stationary-phase reversion of a Lac- frameshift allele in Escherichia coli.

Authors: P L Foster; W A Rosche
Journal: J Bacteriol Date: 1998-04 Impact factor: 3.490

10. Mismatch repair protein MutL becomes limiting during stationary-phase mutation.

Authors: R S Harris; G Feng; K J Ross; R Sidhu; C Thulin; S Longerich; S K Szigety; M E Winkler; S M Rosenberg
Journal: Genes Dev Date: 1997-09-15 Impact factor: 11.361