Literature DB >> 8762155

In search of dihydrofolate reductase.

F M Huennekens1.   

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Year:  1996        PMID: 8762155      PMCID: PMC2143423          DOI: 10.1002/pro.5560050626

Source DB:  PubMed          Journal:  Protein Sci        ISSN: 0961-8368            Impact factor:   6.725


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  9 in total

1.  Increased level of dihydrofolic reductase in leucocytes of patients treated with amethopterin.

Authors:  J R BERTINO; D R DONOHUE; B W GABRIO; R SILBER; A ALENTY; M MEYER; F M HUENNEKENS
Journal:  Nature       Date:  1962-01-13       Impact factor: 49.962

2.  Enzymatic reduction of dihydrofolic acid.

Authors:  M J OSBORN; F M HUENNEKENS
Journal:  J Biol Chem       Date:  1958-10       Impact factor: 5.157

3.  On the enzymic reduction of folic acid by a purified hydrogenase.

Authors:  S F ZAKRZEWSKI; C A NICHOL
Journal:  Biochim Biophys Acta       Date:  1958-02

4.  Inhibition of dihydrofolic reductase by aminopterin and amethopterin.

Authors:  M J OSBORN; M FREEMAN; F M HUENNEKENS
Journal:  Proc Soc Exp Biol Med       Date:  1958-02

5.  On the mechanism of action of aminopterin.

Authors:  C A NICHOL; A D WELCH
Journal:  Proc Soc Exp Biol Med       Date:  1950-06

6.  Water-soluble vitamins concerned with one and two-carbon intermediates.

Authors:  A D WELCH; C A NICHOL
Journal:  Annu Rev Biochem       Date:  1952       Impact factor: 23.643

Review 7.  Karnofsky memorial lecture. Ode to methotrexate.

Authors:  J R Bertino
Journal:  J Clin Oncol       Date:  1993-01       Impact factor: 44.544

8.  Heterologous biosynthesis and processing of preprovasopressin in Neuro2A neuroblastoma cells.

Authors:  F M de Bree; J P Burbach
Journal:  Biochimie       Date:  1994       Impact factor: 4.079

9.  Methotrexate-alpha-phenylalanine: optimization of methotrexate prodrug for activation by carboxypeptidase A-monoclonal antibody conjugate.

Authors:  K S Vitols; B Haag-Zeino; T Baer; Y D Montejano; F M Huennekens
Journal:  Cancer Res       Date:  1995-02-01       Impact factor: 12.701

  9 in total
  9 in total

1.  Essential protein-protein interactions between Plasmodium falciparum thymidylate synthase and dihydrofolate reductase domains.

Authors:  S Shallom; K Zhang; L Jiang; P K Rathod
Journal:  J Biol Chem       Date:  1999-12-31       Impact factor: 5.157

2.  Multiple ligand-binding modes in bacterial R67 dihydrofolate reductase.

Authors:  Hernán Alonso; Malcolm B Gillies; Peter L Cummins; Andrey A Bliznyuk; Jill E Gready
Journal:  J Comput Aided Mol Des       Date:  2005-03       Impact factor: 3.686

3.  X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design.

Authors:  Brad C Bennett; Qun Wan; Md Faiz Ahmad; Paul Langan; Chris G Dealwis
Journal:  J Struct Biol       Date:  2009-05       Impact factor: 2.867

4.  Effects of salt on the structure, stability, and function of a halophilic dihydrofolate reductase from a hyperhalophilic archaeon, Haloarcula japonica strain TR-1.

Authors:  Yurina Miyashita; Eiji Ohmae; Kaoru Nakasone; Katsuo Katayanagi
Journal:  Extremophiles       Date:  2015-01-24       Impact factor: 2.395

5.  Large cosolutes, small cosolutes, and dihydrofolate reductase activity.

Authors:  Luis C Acosta; Gerardo M Perez Goncalves; Gary J Pielak; Annelise H Gorensek-Benitez
Journal:  Protein Sci       Date:  2017-11-17       Impact factor: 6.725

6.  Efficacies of lipophilic inhibitors of dihydrofolate reductase against parasitic protozoa.

Authors:  H Lau; J T Ferlan; V H Brophy; A Rosowsky; C H Sibley
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

7.  Functionally important conformations of the Met20 loop in dihydrofolate reductase are populated by rapid thermal fluctuations.

Authors:  Karunesh Arora; Charles L Brooks Iii
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

8.  High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection.

Authors:  Yusuf Talha Tamer; Ilona K Gaszek; Haleh Abdizadeh; Tugce Altinusak Batur; Kimberly A Reynolds; Ali Rana Atilgan; Canan Atilgan; Erdal Toprak
Journal:  Mol Biol Evol       Date:  2019-07-01       Impact factor: 16.240

Review 9.  Toward a better understanding of folate metabolism in health and disease.

Authors:  Yuxiang Zheng; Lewis C Cantley
Journal:  J Exp Med       Date:  2018-12-26       Impact factor: 14.307

  9 in total

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