Literature DB >> 8755910

Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae.

D Blinder1, P W Coschigano, B Magasanik.   

Abstract

We used cells carrying plasmids causing the overproduction of Gln3p, Ure2p, or both of these proteins to elucidate the ability of Ure2p to prevent the activation of gene expression by Gln3p in cells growing in a glutamine-containing medium. Our results indicate that Ure2p probably does not interfere with the binding of the GATA factor Gln3p to GATAAG sites but acts directly on Gln3p to block its ability to activate transcription.

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Year:  1996        PMID： 8755910      PMCID： PMC178249          DOI： 10.1128/jb.178.15.4734-4736.1996

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  6 in total

1.  Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain.

Authors:  P L Minehart; B Magasanik
Journal:  Mol Cell Biol       Date:  1991-12       Impact factor: 4.272

2.  The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.

Authors:  P W Coschigano; B Magasanik
Journal:  Mol Cell Biol       Date:  1991-02       Impact factor: 4.272

3.  Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene.

Authors:  J R Broach; J N Strathern; J B Hicks
Journal:  Gene       Date:  1979-12       Impact factor: 3.688

4.  Biochemical and physiological aspects of glutamine synthetase inactivation in Saccharomyces cerevisiae.

Authors:  A P Mitchell; B Magasanik
Journal:  J Biol Chem       Date:  1984-10-10       Impact factor: 5.157

5.  Yeast mutants pleiotropically impaired in the regulation of the two glutamate dehydrogenases.

Authors:  R Drillien; M Aigle; F Lacroute
Journal:  Biochem Biophys Res Commun       Date:  1973-07-17       Impact factor: 3.575

6.  Recognition of nitrogen-responsive upstream activation sequences of Saccharomyces cerevisiae by the product of the GLN3 gene.

Authors:  D Blinder; B Magasanik
Journal:  J Bacteriol       Date:  1995-07       Impact factor: 3.490
  6 in total
  56 in total

1.  Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p.

Authors:  K H Cox; R Rai; M Distler; J R Daugherty; J A Coffman; T G Cooper
Journal:  J Biol Chem       Date:  2000-06-09       Impact factor: 5.157

2.  Gln3p nuclear localization and interaction with Ure2p in Saccharomyces cerevisiae.

Authors:  A A Kulkarni; A T Abul-Hamd; R Rai; H El Berry; T G Cooper
Journal:  J Biol Chem       Date:  2001-06-14       Impact factor: 5.157

3.  Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.

Authors:  G K van der Merwe; T G Cooper; H J van Vuuren
Journal:  J Biol Chem       Date:  2001-05-16       Impact factor: 5.157

Review 4.  Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots.

Authors:  Terrance G Cooper
Journal:  FEMS Microbiol Rev       Date:  2002-08       Impact factor: 16.408

5.  The transduction of the nitrogen regulation signal in Saccharomyces cerevisiae.

Authors:  Boris Magasanik
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-07       Impact factor: 11.205

6.  Intranuclear function for protein phosphatase 2A: Pph21 and Pph22 are required for rapamycin-induced GATA factor binding to the DAL5 promoter in yeast.

Authors:  Isabelle Georis; Jennifer J Tate; André Feller; Terrance G Cooper; Evelyne Dubois
Journal:  Mol Cell Biol       Date:  2010-10-25       Impact factor: 4.272

7.  A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae.

Authors:  Julian C Rutherford; Gordon Chua; Timothy Hughes; Maria E Cardenas; Joseph Heitman
Journal:  Mol Biol Cell       Date:  2008-04-23       Impact factor: 4.138

8.  Constitutive and nitrogen catabolite repression-sensitive production of Gat1 isoforms.

Authors:  Rajendra Rai; Jennifer J Tate; Isabelle Georis; Evelyne Dubois; Terrance G Cooper
Journal:  J Biol Chem       Date:  2013-12-09       Impact factor: 5.157

9.  The NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotype.

Authors:  John A Pezza; Sara X Langseth; Rochele Raupp Yamamoto; Stephen M Doris; Samuel P Ulin; Arthur R Salomon; Tricia R Serio
Journal:  Mol Biol Cell       Date:  2008-12-10       Impact factor: 4.138

10.  The [URE3] prion is an aggregated form of Ure2p that can be cured by overexpression of Ure2p fragments.

Authors:  H K Edskes; V T Gray; R B Wickner
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-16       Impact factor: 11.205
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