Literature DB >> 8745398

PROMOTIF--a program to identify and analyze structural motifs in proteins.

E G Hutchinson1, J M Thornton.   

Abstract

We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program currently analyzes the following structural features: secondary structure; beta-and gamma-turns; helical geometry and interactions; beta-strands and beta-sheet topology; beta-bulges; beta-hairpins; beta-alpha-beta units and psi-loops; disulphide bridges; and main-chain hydrogen bonding patterns. PROMOTIF creates postscript files showing the examples of each type of motif in the protein, and a summary page. The program can also be used to compare motifs in a group of related structures, such as an ensemble of NMR structures.

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Year:  1996        PMID: 8745398      PMCID: PMC2143354          DOI: 10.1002/pro.5560050204

Source DB:  PubMed          Journal:  Protein Sci        ISSN: 0961-8368            Impact factor:   6.725


  12 in total

1.  Proteins. One thousand families for the molecular biologist.

Authors:  C Chothia
Journal:  Nature       Date:  1992-06-18       Impact factor: 49.962

2.  Structure of alpha-alpha-hairpins with short connections.

Authors:  A V Efimov
Journal:  Protein Eng       Date:  1991-02

3.  HERA--a program to draw schematic diagrams of protein secondary structures.

Authors:  E G Hutchinson; J M Thornton
Journal:  Proteins       Date:  1990

4.  Structural evidence for gene duplication in the evolution of the acid proteases.

Authors:  J Tang; M N James; I N Hsu; J A Jenkins; T L Blundell
Journal:  Nature       Date:  1978-02-16       Impact factor: 49.962

5.  Analysis and prediction of the different types of beta-turn in proteins.

Authors:  C M Wilmot; J M Thornton
Journal:  J Mol Biol       Date:  1988-09-05       Impact factor: 5.469

6.  Chain reversals in proteins.

Authors:  P N Lewis; F A Momany; H A Scheraga
Journal:  Biochim Biophys Acta       Date:  1973-04-20

7.  One type of gamma-turn, rather than the other gives rise to chain-reversal in proteins.

Authors:  E Milner-White; B M Ross; R Ismail; K Belhadj-Mostefa; R Poet
Journal:  J Mol Biol       Date:  1988-12-05       Impact factor: 5.469

8.  A revised set of potentials for beta-turn formation in proteins.

Authors:  E G Hutchinson; J M Thornton
Journal:  Protein Sci       Date:  1994-12       Impact factor: 6.725

9.  Identification, classification, and analysis of beta-bulges in proteins.

Authors:  A W Chan; E G Hutchinson; D Harris; J M Thornton
Journal:  Protein Sci       Date:  1993-10       Impact factor: 6.725

10.  Crystallographic refinement and structure of DNase I at 2 A resolution.

Authors:  C Oefner; D Suck
Journal:  J Mol Biol       Date:  1986-12-05       Impact factor: 5.469

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  273 in total

1.  PDBsum: summaries and analyses of PDB structures.

Authors:  R A Laskowski
Journal:  Nucleic Acids Res       Date:  2001-01-01       Impact factor: 16.971

2.  Solution structure of a defensin-like peptide from platypus venom.

Authors:  A M Torres; X Wang; J I Fletcher; D Alewood; P F Alewood; R Smith; R J Simpson; G M Nicholson; S K Sutherland; C H Gallagher; G F King; P W Kuchel
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

3.  Barrel structures in proteins: automatic identification and classification including a sequence analysis of TIM barrels.

Authors:  N Nagano; E G Hutchinson; J M Thornton
Journal:  Protein Sci       Date:  1999-10       Impact factor: 6.725

4.  The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.

Authors:  D R Hall; D G Gourley; G A Leonard; E M Duke; L A Anderson; D H Boxer; W N Hunter
Journal:  EMBO J       Date:  1999-03-15       Impact factor: 11.598

5.  Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor.

Authors:  K M McBride; C McDonald; N C Reich
Journal:  EMBO J       Date:  2000-11-15       Impact factor: 11.598

6.  Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases.

Authors:  R D Scavetta; C B Thomas; M A Walsh; S Szegedi; A Joachimiak; R I Gumport; M E Churchill
Journal:  Nucleic Acids Res       Date:  2000-10-15       Impact factor: 16.971

7.  NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus).

Authors:  A M Torres; R M Kini; N Selvanayagam; P W Kuchel
Journal:  Biochem J       Date:  2001-12-15       Impact factor: 3.857

8.  Solution structure and stability of the anti-sigma factor AsiA: implications for novel functions.

Authors:  Jeffrey L Urbauer; Mario F Simeonov; Ramona J Bieber Urbauer; Karen Adelman; Joshua M Gilmore; Edward N Brody
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-05       Impact factor: 11.205

9.  Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus.

Authors:  C S Bond; M Kvaratskhelia; D Richard; M F White; W N Hunter
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-01       Impact factor: 11.205

10.  A neural-network based method for prediction of gamma-turns in proteins from multiple sequence alignment.

Authors:  Harpreet Kaur; G P S Raghava
Journal:  Protein Sci       Date:  2003-05       Impact factor: 6.725

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