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Literature DB >> 873322

Enterochromaffin cells in the duodenal mucosa of children with coeliac disease.

Abstract

A cell counting technique was used to count enterochromaffin (EC) cells in the duodenal mucosa of 10 children with coeliac disease and 10 controls, and significantly greater numbers of EC cells were found in children with coeliac disease. In four children with a clinical history suggestive of coeliac disease, but with minor histopathological changes in the duodenum, gluten challenge resulted in increased numbers of EC cells. Abnormalities of 5-hydroxytryptamine metabolism in coeliac disease may result from hyperplasia of EC cells in the small intestine.

Entities: Chemical Disease Species

Mesh：

Substances：
Glutens

Year: 1977 PMID： 873322 PMCID： PMC1411490 DOI： 10.1136/gut.18.5.373

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

17 in total

Enterochromaffin cells in the duodenal mucosa of children with coeliac disease.

1. ABNORMAL TRYPTOPHAN METABOLISM IN PATIENTS WITH ADULT CELIAC DISEASE, WITH EVIDENCE FOR DEFICIENCY OF VITAMIN B6.

Review 2. ADULT CELIAC DISEASE WITH EMPHASIS UPON RESPONSE TO THE GLUTEN-FREE DIET.

3. Abnormalities of tryptophan metabolism in a patient with malabsorption syndrome.

4. Principles and methods for the morphometric study of the lung and other organs.

5. Indole metabolism in the malabsorption syndrome.

6. Blood serotonin in nontropical sprue.

7. Serotonin and the gastrointestinal tract.

8. Urinary excretion of 5-hydroxyindolacetic acid in diarrheal states, with special reference to nontropical sprue.

9. Quantitation of G-cells in fibreoptic biopsy specimens and serum gastrin levels in healthy normal subjects.

10. Urinary 5-hydroxyindoleacetic acid in 8-hour collections as an aid in diagnosis of coeliac disease.

1. Overrepresentation of HLA-DQ2 in small intestinal neuroendocrine tumor patients.

Review 2. Hyperplastic proliferations of enteroendocrine cells.

3. Quantification of enterochromaffin cells with serotonin immunoreactivity in the duodenal mucosa in coeliac disease.

4. Increased tissue concentrations of 5-hydroxytryptamine in the duodenal mucosa of patients with coeliac disease.

5. Raised 5-hydroxytryptamine concentrations in enterochromaffin cells in adult coeliac disease.

6. Duodenal endocrine cells in adult coeliac disease.

7. Enteropathy of coeliac disease in adults: increased number of enterochromaffin cells the duodenal mucosa.

Review 8. The relation between celiac disease, nonceliac gluten sensitivity and irritable bowel syndrome.