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Literature DB >> 590848

Increased tissue concentrations of 5-hydroxytryptamine in the duodenal mucosa of patients with coeliac disease.

Abstract

Tissue concentrations of 5-HT have been measured in the duodenal mucosa of adults and children with coeliac disease and were found to be significantly higher than those from a control group. This finding may be associated with hyperactivity or hyperplasia of enterochromaffin (EC) cells in the duodenum of patients with coeliac disease and could also be directly related to described abnormalities of 5-HT metabolism in this disease.

Entities: Chemical Disease Species

Mesh：

Substances：
Serotonin
Glutens

Year: 1977 PMID： 590848 PMCID： PMC1411730 DOI： 10.1136/gut.18.11.882

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

19 in total

1. ABNORMAL TRYPTOPHAN METABOLISM IN PATIENTS WITH ADULT CELIAC DISEASE, WITH EVIDENCE FOR DEFICIENCY OF VITAMIN B6.

Authors: O D KOWLESSAR; L J HAEFFNER; G D BENSON
Journal: J Clin Invest Date: 1964-05 Impact factor: 14.808

Review 2. ADULT CELIAC DISEASE WITH EMPHASIS UPON RESPONSE TO THE GLUTEN-FREE DIET.

Authors: G D BENSON; O D KOWLESSAR; M H SLEISENGER
Journal: Medicine (Baltimore) Date: 1964-01 Impact factor: 1.889

3. Blood serotonin in malabsorption states.

Authors: R R WARNER; N COHEN
Journal: Am J Dig Dis Date: 1962-06

4. Abnormalities of tryptophan metabolism in a patient with malabsorption syndrome.

Authors: C R SCRIVER
Journal: J Lab Clin Med Date: 1961-12

5. Indole metabolism in the malabsorption syndrome.

Authors: B J HAVERBACK; B DYCE; H V THOMAS
Journal: N Engl J Med Date: 1960-04-14 Impact factor: 91.245

6. Blood serotonin in nontropical sprue.

Authors: B D PIMPARKAR; D SENESKY; M H KALSER
Journal: Gastroenterology Date: 1961-04 Impact factor: 22.682

7. Serotonin and the gastrointestinal tract.

Authors: B J HAVERBACK; J D DAVIDSON
Journal: Gastroenterology Date: 1958-12 Impact factor: 22.682

8. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

9. Enterochromaffin cells in the duodenal mucosa of children with coeliac disease.

Authors: D N Challacombe; K Robertson
Journal: Gut Date: 1977-05 Impact factor: 23.059

10. Urinary 5-hydroxyindoleacetic acid in 8-hour collections as an aid in diagnosis of coeliac disease.

Authors: D N Challacombe; M Goodall; H Gaze; G A Brown
Journal: Arch Dis Child Date: 1975-10 Impact factor: 3.791

13 in total

1. Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders.

Authors: Hirotada Akiho; Eikichi Ihara; Yasuaki Motomura; Kazuhiko Nakamura
Journal: World J Gastrointest Pathophysiol Date: 2011-10-15

Review 2. Hyperplastic proliferations of enteroendocrine cells.

Authors: Yogeshwar Dayal
Journal: Endocr Pathol Date: 1994-03 Impact factor: 3.943

3. Quantification of enterochromaffin cells with serotonin immunoreactivity in the duodenal mucosa in coeliac disease.

Authors: E E Wheeler; D N Challacombe
Journal: Arch Dis Child Date: 1984-06 Impact factor: 3.791

4. Influence of 5-hydroxytryptamine on crypt cell production rate of human duodenal mucosa cultured in vitro.

Authors: E E Wheeler; D N Challacombe
Journal: J Clin Pathol Date: 1987-07 Impact factor: 3.411

5. Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.

Authors: Ravinder K Gill; Le Shen; Jerrold R Turner; Seema Saksena; Waddah A Alrefai; Nitika Pant; Ali Esmaili; Alka Dwivedi; Krishnamurthy Ramaswamy; Pradeep K Dudeja
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2008-07-31 Impact factor: 4.052