Literature DB >> 8725221

Destabilization of simple repetitive DNA sequences by transcription in yeast.

M Wierdl1, C N Greene, A Datta, S Jinks-Robertson, T D Petes.   

Abstract

Simple repetitive DNA sequences in the eukaryotic genome frequently alter in length. In wild-type strains, we find that transcription through a repetitive poly GT tract destabilizes the tract four- to ninefold. In mismatch repair-deficient yeast strains, simple repeats are very unstable. High levels of transcription in such strains destabilize repetitive tracts an additional two- to threefold.

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Year:  1996        PMID： 8725221      PMCID： PMC1207331     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  32 in total

1.  Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday.

Authors:  G Streisinger; Y Okada; J Emrich; J Newton; A Tsugita; E Terzaghi; M Inouye
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1966

2.  A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication.

Authors:  K A Jones; J T Kadonaga; P J Rosenfeld; T J Kelly; R Tjian
Journal:  Cell       Date:  1987-01-16       Impact factor: 41.582

3.  Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

Authors:  M Strand; M C Earley; G F Crouse; T D Petes
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

4.  Simple sequences are ubiquitous repetitive components of eukaryotic genomes.

Authors:  D Tautz; M Renz
Journal:  Nucleic Acids Res       Date:  1984-05-25       Impact factor: 16.971

5.  Cryptic simplicity in DNA is a major source of genetic variation.

Authors:  D Tautz; M Trick; G A Dover
Journal:  Nature       Date:  1986 Aug 14-20       Impact factor: 49.962

6.  Construction of LYS2 cartridges for use in genetic manipulations of Saccharomyces cerevisiae.

Authors:  U N Fleig; R D Pridmore; P Philippsen
Journal:  Gene       Date:  1986       Impact factor: 3.688

7.  Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

Authors:  M Johnston; R W Davis
Journal:  Mol Cell Biol       Date:  1984-08       Impact factor: 4.272

8.  High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12.

Authors:  G Levinson; G A Gutman
Journal:  Nucleic Acids Res       Date:  1987-07-10       Impact factor: 16.971

9.  A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes.

Authors:  H Hamada; M G Petrino; T Kakunaga
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

10.  Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

Authors:  R R Yocum; S Hanley; R West; M Ptashne
Journal:  Mol Cell Biol       Date:  1984-10       Impact factor: 4.272
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  56 in total

1.  Mechanisms of dinucleotide repeat instability in Escherichia coli.

Authors:  M Bichara; I Pinet; S Schumacher; R P Fuchs
Journal:  Genetics       Date:  2000-02       Impact factor: 4.562

Review 2.  Determining mutation rates in bacterial populations.

Authors:  W A Rosche; P L Foster
Journal:  Methods       Date:  2000-01       Impact factor: 3.608

3.  Tandem repeat recombination induced by replication fork defects in Escherichia coli requires a novel factor, RadC.

Authors:  C J Saveson; S T Lovett
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

4.  Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast.

Authors:  E A Sia; M Dominska; L Stefanovic; T D Petes
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

5.  New insights into repeat instability: role of RNA•DNA hybrids.

Authors:  Elizabeth I McIvor; Urszula Polak; Marek Napierala
Journal:  RNA Biol       Date:  2010-09-01       Impact factor: 4.652

6.  Methods for determining spontaneous mutation rates.

Authors:  Patricia L Foster
Journal:  Methods Enzymol       Date:  2006       Impact factor: 1.600

7.  Variation in efficiency of DNA mismatch repair at different sites in the yeast genome.

Authors:  Joshua D Hawk; Lela Stefanovic; Jayne C Boyer; Thomas D Petes; Rosann A Farber
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-02       Impact factor: 11.205

8.  Transcription increases the deletion frequency of long CTG.CAG triplet repeats from plasmids in Escherichia coli.

Authors:  R P Bowater; A Jaworski; J E Larson; P Parniewski; R D Wells
Journal:  Nucleic Acids Res       Date:  1997-07-15       Impact factor: 16.971

9.  Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast.

Authors:  A Datta; M Hendrix; M Lipsitch; S Jinks-Robertson
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205

10.  Triplet repeats form secondary structures that escape DNA repair in yeast.

Authors:  H Moore; P W Greenwell; C P Liu; N Arnheim; T D Petes
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-16       Impact factor: 11.205
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