Literature DB >> 8719780

Endothelium-dependent relaxation to the B1 kinin receptor agonist des-Arg9-bradykinin in human coronary arteries.

G R Drummond1, T M Cocks.   

Abstract

Des-Arg9-bradykinin (des-Arg9-BK) caused endothelium-dependent relaxations in human, isolated coronary arteries which upregulated with in vitro incubation time. Relaxations to des-Arg9-BK were inhibited by the B1 receptor antagonist, des-Arg9-[Leu3]-BK (pK(B), 6.14 +/- 0.11) but were unaffected by the B2 receptor antagonist, Hoe-140. Therefore, this is the first demonstration that human coronary arteries possess endothelial B1 receptors which mediate endothelium-dependent relaxation and appear to be synthesized de novo during the incubation period.

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Year:  1995        PMID： 8719780      PMCID： PMC1909186          DOI： 10.1111/j.1476-5381.1995.tb15108.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  7 in total

1.  Characterization and function of bradykinin receptors in vascular endothelial cells.

Authors:  C P Sung; A J Arleth; K Shikano; B A Berkowitz
Journal:  J Pharmacol Exp Ther       Date:  1988-10       Impact factor: 4.030

2.  Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery.

Authors:  E Kimura; K Hashimoto; S Furukawa; H Hayakawa
Journal:  Am Heart J       Date:  1973-05       Impact factor: 4.749

3.  Induction of bradykinin B1 receptor-mediated relaxation in the isolated rabbit carotid artery.

Authors:  D Pruneau; P Bélichard
Journal:  Eur J Pharmacol       Date:  1993-08-03       Impact factor: 4.432

4.  [Cardiac dysfunction and endogenous cytokines in global ischemia and reperfusion injury].

Authors:  Y Kamikubo
Journal:  Hokkaido Igaku Zasshi       Date:  1993-11

5.  Pharmacological reactivity of human epicardial coronary arteries: phasic and tonic responses to vasoconstrictor agents differentiated by nifedipine.

Authors:  A P Stork; T M Cocks
Journal:  Br J Pharmacol       Date:  1994-12       Impact factor: 8.739

6.  Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor.

Authors:  A P Stork; T M Cocks
Journal:  Br J Pharmacol       Date:  1994-12       Impact factor: 8.739

7.  Relaxation of isolated mesenteric arteries by des-Arg9-bradykinin stimulation of B1 receptors.

Authors:  L Churchill; P E Ward
Journal:  Eur J Pharmacol       Date:  1986-10-14       Impact factor: 4.432
  7 in total
  10 in total

Review 1.  Kinin receptors.

Authors:  F Marceau; D R Bachvarov
Journal:  Clin Rev Allergy Immunol       Date:  1998       Impact factor: 8.667

2.  Endotoxin sensitization to kinin B(1) receptor agonist in a non-human primate model: haemodynamic and pro-inflammatory effects.

Authors:  D deBlois; R A Horlick
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

3.  Functional evidence of des-Arg10-kallidin enzymatic inactivating pathway in isolated human umbilical vein.

Authors:  Wanda Nowak; Ezequiel Dario Goldschmidt; Alejandra Georgina Falcioni; Mariana Ines Pugliese; Andrea Emilse Errasti; Facundo German Pelorosso; Federico Manuel Daray; Juan Ezequiel Gago; Rodolfo Pedro Rothlin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2007-03-20       Impact factor: 3.000

4.  Protease-activated receptor-2 turnover stimulated independently of receptor activation in porcine coronary endothelial cells.

Authors:  J R Hamilton; J M Chow; T M Cocks
Journal:  Br J Pharmacol       Date:  1999-06       Impact factor: 8.739

Review 5.  ACE inhibition, endothelial function and coronary artery lesions. Role of kinins and nitric oxide.

Authors:  J V Mombouli
Journal:  Drugs       Date:  1997       Impact factor: 9.546

6.  Vasomotor and fibrinolytic responses to kinin receptor agonists in the atherosclerotic human lower limb.

Authors:  Nicholas L M Cruden; Ninian N Lang; Thomas J MacGillivray; Neal G Uren; Keith A A Fox; David E Newby
Journal:  Heart Vessels       Date:  2011-03-11       Impact factor: 2.037

7.  Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation.

Authors:  P G McLean; M Perretti; A Ahluwalia
Journal:  Br J Pharmacol       Date:  1999-09       Impact factor: 8.739

8.  gC1qR Antibody Can Modulate Endothelial Cell Permeability in Angioedema.

Authors:  Marina Fandaros; Kusumam Joseph; Allen P Kaplan; David A Rubenstein; Berhane Ghebrehiwet; Wei Yin
Journal:  Inflammation       Date:  2021-09-07       Impact factor: 4.092

9.  ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries.

Authors:  Kathryn M Gauthier; Cody J Cepura; William B Campbell
Journal:  Biol Chem       Date:  2013-09       Impact factor: 3.915

10.  Gene Variant of the Bradykinin B2 Receptor Influences Pulmonary Arterial Pressures in Heart Failure Patients.

Authors:  Thomas P Olson; Robert P Frantz; Stephen T Turner; Kent R Bailey; Christina M Wood; Bruce D Johnson
Journal:  Clin Med Circ Respirat Pulm Med       Date:  2009-02-17
  10 in total

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