Literature DB >> 869543

Production and antibacterial activity of malforming C, a toxic metabolite of Aspergillus niger.

B Kobbe, M Cushman, G N Wogan, A L Demain.   

Abstract

The production of the new mycotoxin malformin C by a solid substrate fermentation is described. Malformin C is highly toxic (mean lethal dose = 0.9 mg/kg) and exerts antibacterial activity against a variety of gram-positive and gram-negative organisms.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 869543      PMCID： PMC170807          DOI： 10.1128/aem.33.4.996-997.1977

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  7 in total

1.  Isolation & characterization of malformin.

Authors:  N Takahashi; R W Curtis
Journal:  Plant Physiol       Date:  1961-01       Impact factor: 8.340

2.  Studies on response of bean seedlings & corn roots to malformin.

Authors:  R W Curtis
Journal:  Plant Physiol       Date:  1961-01       Impact factor: 8.340

3.  Malformin C, a new metabolite of Aspergillus niger.

Authors:  R J Anderegg; K Biemann; G Büchi; M Cushman
Journal:  J Am Chem Soc       Date:  1976-05-26       Impact factor: 15.419

4.  Improved procedure for production of cytochalasin E and tremorgenic mycotoxins by Aspergillus clavatus.

Authors:  A L Demain; N A Hunt; V Malik; B Kobbe; H Hawkins; K Matsuo; G N Wogan
Journal:  Appl Environ Microbiol       Date:  1976-01       Impact factor: 4.792

5.  Trace metal requirements for malformin biosynthesis.

Authors:  S T Steenbergen; E D Weinberg
Journal:  Growth       Date:  1968-06

6.  Effect of mycotoxins and coumarins on the growth of Bacillus megaterium from spores.

Authors:  A R Buckelew; A Chakravarti; W R Burge; V M Thomas; M Ikawa
Journal:  J Agric Food Chem       Date:  1972 Mar-Apr       Impact factor: 5.279

7.  Antibiotic properties of malformin.

Authors:  S Suda; R W Curtis
Journal:  Appl Microbiol       Date:  1966-05
  7 in total
  10 in total

1.  Hematological and biochemical changes in rats administered with Aspergillus niger infested diet.

Authors:  V Tiwari; R K Chauhan
Journal:  Bull Environ Contam Toxicol       Date:  1992-04       Impact factor: 2.151

2.  Mycotoxin-producing fungi isolated from bin-stored corn.

Authors:  V Sanchis; I Viñas; M Jimenez; M A Calvo; E Hernandez
Journal:  Mycopathologia       Date:  1982-11-19       Impact factor: 2.574

3.  Solid state fermentation for cephalosporin production by Streptomyces clavuligerus and Cephalosporium acremonium.

Authors:  M F Jermini; A L Demain
Journal:  Experientia       Date:  1989-12-01

Review 4.  Antiviral Peptides (AVPs) of Marine Origin as Propitious Therapeutic Drug Candidates for the Treatment of Human Viruses.

Authors:  Linda Sukmarini
Journal:  Molecules       Date:  2022-04-19       Impact factor: 4.927

5.  Toxic aspergilli from pistachio nuts.

Authors:  H Mojtahedi; C J Rabie; A Lübben; M Steyn; D Danesh
Journal:  Mycopathologia       Date:  1979-05-31       Impact factor: 2.574

Review 6.  Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.

Authors:  Jens C Frisvad; Lars L H Møller; Thomas O Larsen; Ravi Kumar; José Arnau
Journal:  Appl Microbiol Biotechnol       Date:  2018-10-06       Impact factor: 4.813

7.  Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism.

Authors:  Louise M Sørensen; Rene Lametsch; Mikael R Andersen; Per V Nielsen; Jens C Frisvad
Journal:  BMC Microbiol       Date:  2009-12-10       Impact factor: 3.605

8.  Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug.

Authors:  Jing Wang; Zaoli Jiang; Wing Lam; Elizabeth A Gullen; Zhe Yu; Ying Wei; Lihui Wang; Caroline Zeiss; Amanda Beck; Ee-Chun Cheng; Chunfu Wu; Yung-Chi Cheng; Yixuan Zhang
Journal:  PLoS One       Date:  2015-11-05       Impact factor: 3.240

9.  Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity.

Authors:  Yukio Koizumi; Kenichiro Nagai; Lina Gao; Souichi Koyota; Tomokazu Yamaguchi; Miyuki Natsui; Yumiko Imai; Keiji Hasumi; Toshihiro Sugiyama; Keiji Kuba
Journal:  Sci Rep       Date:  2018-04-03       Impact factor: 4.379

10.  Calm Before the Storm: A Glimpse into the Secondary Metabolism of Aspergillus welwitschiae, the Etiologic Agent of the Sisal Bole Rot.

Authors:  Gabriel Quintanilha-Peixoto; Rosimére Oliveira Torres; Isabella Mary Alves Reis; Thiago Alves Santos de Oliveira; Dener Eduardo Bortolini; Elizabeth Amélia Alves Duarte; Vasco Ariston de Carvalho Azevedo; Bertram Brenig; Eric Roberto Guimarães Rocha Aguiar; Ana Cristina Fermino Soares; Aristóteles Góes-Neto; Alexsandro Branco
Journal:  Toxins (Basel)       Date:  2019-10-30       Impact factor: 4.546
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.