Literature DB >> 8675349

Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.

M J Alfa1, P DeGagne, P A Totten.   

Abstract

Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, produces several factors that damage human cells. We used isogenic mutants of H. ducreyi 35000 to demonstrate that the hemolytic activity and the cytotoxic effect of H. ducreyi on human foreskin fibroblasts are due to the same toxin.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8675349      PMCID： PMC174078          DOI： 10.1128/iai.64.6.2349-2352.1996

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

1.  Haemophilus ducreyi, a cytotoxin-producing bacterium.

Authors:  M Purvén; T Lagergård
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

Review 2.  Pore-forming cytolysins of gram-negative bacteria.

Authors:  R A Welch
Journal:  Mol Microbiol       Date:  1991-03       Impact factor: 3.501

3.  Cytopathic effect of Haemophilus ducreyi for human foreskin cell culture.

Authors:  M J Alfa
Journal:  J Med Microbiol       Date:  1992-07       Impact factor: 2.472

4.  Chancroid in the United States, 1981-1990: evidence for underreporting of cases.

Authors:  J M Schulte; F A Martich; G P Schmid
Journal:  MMWR CDC Surveill Summ       Date:  1992-05-29

Review 5.  Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases.

Authors:  J N Wasserheit
Journal:  Sex Transm Dis       Date:  1992 Mar-Apr       Impact factor: 2.830

6.  Characterization of the hemolytic activity of Haemophilus ducreyi.

Authors:  P A Totten; D V Norn; W E Stamm
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

7.  Cytotoxic activity of the Proteus hemolysin HpmA.

Authors:  K G Swihart; R A Welch
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

8.  Cloning and characterization of the genes encoding the hemolysin of Haemophilus ducreyi.

Authors:  K L Palmer; R S Munson
Journal:  Mol Microbiol       Date:  1995-12       Impact factor: 3.501

9.  A temperature-dependent rabbit model for production of dermal lesions by Haemophilus ducreyi.

Authors:  B K Purcell; J A Richardson; J D Radolf; E J Hansen
Journal:  J Infect Dis       Date:  1991-08       Impact factor: 5.226

10.  Cofactors in male-female sexual transmission of human immunodeficiency virus type 1.

Authors:  F A Plummer; J N Simonsen; D W Cameron; J O Ndinya-Achola; J K Kreiss; M N Gakinya; P Waiyaki; M Cheang; P Piot; A R Ronald
Journal:  J Infect Dis       Date:  1991-02       Impact factor: 5.226
View more
  27 in total

1.  The LspB protein is involved in the secretion of the LspA1 and LspA2 proteins by Haemophilus ducreyi.

Authors:  Christine K Ward; Jason R Mock; Eric J Hansen
Journal:  Infect Immun       Date:  2004-04       Impact factor: 3.441

2.  Identification of tandem genes involved in lipooligosaccharide expression by Haemophilus ducreyi.

Authors:  M K Stevens; J Klesney-Tait; S Lumbley; K A Walters; A M Joffe; J D Radolf; E J Hansen
Journal:  Infect Immun       Date:  1997-02       Impact factor: 3.441

3.  Cloning and characterization of the lipooligosaccharide galactosyltransferase II gene of Haemophilus ducreyi.

Authors:  S Sun; B Schilling; L Tarantino; M V Tullius; B W Gibson; R S Munson
Journal:  J Bacteriol       Date:  2000-04       Impact factor: 3.490

4.  Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi.

Authors:  K L Thomas; I Leduc; B Olsen; C E Thomas; D W Cameron; C Elkins
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

5.  Molecular characterization of the interaction of sialic acid with the periplasmic binding protein from Haemophilus ducreyi.

Authors:  Thanuja Gangi Setty; Jonathan C Mowers; Aaron G Hobbs; Shubha P Maiya; Sanaa Syed; Robert S Munson; Michael A Apicella; Ramaswamy Subramanian
Journal:  J Biol Chem       Date:  2018-10-12       Impact factor: 5.157

6.  Identification of a novel sialic acid transporter in Haemophilus ducreyi.

Authors:  Deborah M B Post; Rachna Mungur; Bradford W Gibson; Robert S Munson
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

7.  Purification and identification of Haemophilus ducreyi cytotoxin by use of a neutralizing monoclonal antibody.

Authors:  M Purvén; A Frisk; I Lönnroth; T Lagergard
Journal:  Infect Immun       Date:  1997-08       Impact factor: 3.441

8.  Involvement of the Haemophilus ducreyi gmhA gene product in lipooligosaccharide expression and virulence.

Authors:  B A Bauer; M K Stevens; E J Hansen
Journal:  Infect Immun       Date:  1998-09       Impact factor: 3.441

9.  Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins.

Authors:  Merja Vakevainen; Steven Greenberg; Eric J Hansen
Journal:  Infect Immun       Date:  2003-10       Impact factor: 3.441

10.  A CdtA-CdtC complex can block killing of HeLa cells by Haemophilus ducreyi cytolethal distending toxin.

Authors:  Kaiping Deng; Eric J Hansen
Journal:  Infect Immun       Date:  2003-11       Impact factor: 3.441
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.