OBJECTIVE: To evaluate the effect of weight loss induced by dietetic treatment, with or without an intragastric balloon, on gastric emptying of obese subjects. SUBJECTS: 20 morbidly obese subjects (21-54 years, 45.3-58.0 kg/m2) and 20 healthy controls (21-56 years, 20.3-24.8 kg/m2). DESIGN: Parallel study of a 4 month, low calorie dietetic treatment with or without a 500 ml intragastric balloon. RESULTS: In basal conditions, obese subjects had accelerated gastric emptying as compared to healthy controls. At the end of the dietetic treatment period, a significant decrease of body weight was obtained. Patients also showed a slowing of gastric emptying. Both the weight loss and the slowing of gastric emptying occurred irrespective of the presence or absence of the intragastric balloon. CONCLUSION: The present findings are compatible with the hypothesis that gastric emptying, food intake and body weight are integrated parameters in subjects with morbid obesity.
OBJECTIVE: To evaluate the effect of weight loss induced by dietetic treatment, with or without an intragastric balloon, on gastric emptying of obese subjects. SUBJECTS: 20 morbidly obese subjects (21-54 years, 45.3-58.0 kg/m2) and 20 healthy controls (21-56 years, 20.3-24.8 kg/m2). DESIGN: Parallel study of a 4 month, low calorie dietetic treatment with or without a 500 ml intragastric balloon. RESULTS: In basal conditions, obese subjects had accelerated gastric emptying as compared to healthy controls. At the end of the dietetic treatment period, a significant decrease of body weight was obtained. Patients also showed a slowing of gastric emptying. Both the weight loss and the slowing of gastric emptying occurred irrespective of the presence or absence of the intragastric balloon. CONCLUSION: The present findings are compatible with the hypothesis that gastric emptying, food intake and body weight are integrated parameters in subjects with morbid obesity.
Authors: Hrair P Simonian; Kashyap Panganamamula; Henry P Parkman; Xiaohong Xu; Jiande Z Chen; Greger Lindberg; Hui Xu; Chi Shao; Mei-Yun Ke; Michael Lykke; Per Hansen; Bjorn Barner; Henrik Buhl Journal: Dig Dis Sci Date: 2004-04 Impact factor: 3.199
Authors: A E Bharucha; A Manduca; D S Lake; J Fidler; P Edwards; R C Grimm; A R Zinsmeister; S J Riederer Journal: Neurogastroenterol Motil Date: 2011-04-06 Impact factor: 3.598
Authors: Paul S Maclean; Audrey Bergouignan; Marc-Andre Cornier; Matthew R Jackman Journal: Am J Physiol Regul Integr Comp Physiol Date: 2011-06-15 Impact factor: 3.619
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Authors: John Melissas; Markos Daskalakis; Sophia Koukouraki; Ioannis Askoxylakis; Maria Metaxari; Efstathios Dimitriadis; Maria Stathaki; John A Papadakis Journal: Obes Surg Date: 2008-07-29 Impact factor: 4.129